Entity Details

Primary name THIL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8QZT1
EntryNameTHIL_MOUSE
FullNameAcetyl-CoA acetyltransferase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length424
SequenceStatuscomplete
DateCreated2004-09-13
DateModified2021-06-02

Ontological Relatives

GenesAcat1

GO terms

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GOName
GO:0001889 liver development
GO:0003985 acetyl-CoA C-acetyltransferase activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006085 acetyl-CoA biosynthetic process
GO:0006550 isoleucine catabolic process
GO:0006635 fatty acid beta-oxidation
GO:0007420 brain development
GO:0009725 response to hormone
GO:0014070 response to organic cyclic compound
GO:0015936 coenzyme A metabolic process
GO:0015937 coenzyme A biosynthetic process
GO:0016453 C-acetyltransferase activity
GO:0019899 enzyme binding
GO:0030955 potassium ion binding
GO:0042594 response to starvation
GO:0042802 identical protein binding
GO:0046356 acetyl-CoA catabolic process
GO:0046952 ketone body catabolic process
GO:0060612 adipose tissue development
GO:0072229 metanephric proximal convoluted tubule development
GO:0120225 coenzyme A binding
GO:1902860 propionyl-CoA biosynthetic process

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR002155 ThiolaseFamilyFamily
IPR016039 Thiolase-likeFamilyHomologous superfamily
IPR020610 Thiolase, active siteSiteActive site
IPR020613 Thiolase, conserved siteSiteConserved site
IPR020615 Thiolase, acyl-enzyme intermediate active siteSiteActive site
IPR020616 Thiolase, N-terminalDomainDomain
IPR020617 Thiolase, C-terminalDomainDomain

Diseases

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Interactions

3 interactions