Entity Details

Primary name E2F4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8R0K9
EntryNameE2F4_MOUSE
FullNameTranscription factor E2F4
TaxID10090
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesE2f4

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001216 DNA-binding transcription activator activity
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002064 epithelial cell development
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006884 cell volume homeostasis
GO:0008015 blood circulation
GO:0008134 transcription factor binding
GO:0008361 regulation of cell size
GO:0009887 animal organ morphogenesis
GO:0019904 protein domain specific binding
GO:0042127 regulation of cell population proliferation
GO:0044458 motile cilium assembly
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0051726 regulation of cell cycle
GO:0060271 cilium assembly
GO:0090575 RNA polymerase II transcription regulator complex
GO:0098534 centriole assembly
GO:1903251 multi-ciliated epithelial cell differentiation
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003316 E2F/DP family, winged-helix DNA-binding domainDomainDomain
IPR015633 E2F FamilyFamilyFamily
IPR028312 Transcription factor E2F4FamilyFamily
IPR032198 E2F transcription factor, CC-MB domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037241 E2F-DP heterodimerization regionFamilyHomologous superfamily

Diseases

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