Entity Details

Primary name SPTC1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35704
EntryNameSPTC1_MOUSE
FullNameSerine palmitoyltransferase 1
TaxID10090
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSptlc1

GO terms

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GOName
GO:0004758 serine C-palmitoyltransferase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006665 sphingolipid metabolic process
GO:0006686 sphingomyelin biosynthetic process
GO:0016021 integral component of membrane
GO:0017059 serine C-palmitoyltransferase complex
GO:0030148 sphingolipid biosynthetic process
GO:0030170 pyridoxal phosphate binding
GO:0035339 SPOTS complex
GO:0046511 sphinganine biosynthetic process
GO:0046512 sphingosine biosynthetic process
GO:0046513 ceramide biosynthetic process
GO:1904504 positive regulation of lipophagy
GO:1904649 regulation of fat cell apoptotic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR004839 Aminotransferase, class I/classIIDomainDomain
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SPTC1_MOUSEABCA1_MOUSEBioGRID18484747 details
SPTC1_MOUSEPARD3_MOUSEBioGRID18484747 details