Entity Details

Primary name PLCD1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8R3B1
EntryNamePLCD1_MOUSE
FullName1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
TaxID10090
Evidenceevidence at protein level
Length756
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesPlcd1

GO terms

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GOName
GO:0001525 angiogenesis
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004629 phospholipase C activity
GO:0005509 calcium ion binding
GO:0005543 phospholipid binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007186 G protein-coupled receptor signaling pathway
GO:0010701 positive regulation of norepinephrine secretion
GO:0016020 membrane
GO:0016042 lipid catabolic process
GO:0031966 mitochondrial membrane
GO:0032794 GTPase activating protein binding
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process
GO:0042127 regulation of cell population proliferation
GO:0043434 response to peptide hormone
GO:0045121 membrane raft
GO:0046488 phosphatidylinositol metabolic process
GO:0048015 phosphatidylinositol-mediated signaling
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051592 response to calcium ion
GO:0060716 labyrinthine layer blood vessel development
GO:0070300 phosphatidic acid binding
GO:0070679 inositol 1,4,5 trisphosphate binding
GO:1900274 regulation of phospholipase C activity
GO:1901981 phosphatidylinositol phosphate binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000909 Phosphatidylinositol-specific phospholipase C, X domainDomainDomain
IPR001192 Phosphoinositide phospholipase C familyFamilyFamily
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015359 Phosphoinositide-specific phospholipase C, EF-hand-like domainDomainDomain
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamilyFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR028391 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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