Search
News
Downloads
About
Help
Contact
Entity Details
Primary name
IRAK4_MOUSE
Entity type
UniProt
Source
Source Link
Details
Accession
Q8R4K2
EntryName
IRAK4_MOUSE
FullName
Interleukin-1 receptor-associated kinase 4
TaxID
10090
Evidence
evidence at protein level
Length
459
SequenceStatus
complete
DateCreated
2004-07-19
DateModified
2021-06-02
Ontological Relatives
Genes
Irak4
GO terms
Show/Hide Table
GO
Name
GO:0000287
magnesium ion binding
GO:0002446
neutrophil mediated immunity
GO:0004672
protein kinase activity
GO:0004674
protein serine/threonine kinase activity
GO:0005149
interleukin-1 receptor binding
GO:0005524
ATP binding
GO:0005615
extracellular space
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005886
plasma membrane
GO:0007254
JNK cascade
GO:0019221
cytokine-mediated signaling pathway
GO:0035556
intracellular signal transduction
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087
innate immune response
GO:0048661
positive regulation of smooth muscle cell proliferation
GO:0106310
protein serine kinase activity
GO:0106311
protein threonine kinase activity
GO:1990266
neutrophil migration
Subcellular Location
Show/Hide Table
Subcellular Location
Cytoplasm
Domains
Show/Hide Table
Domain
Name
Category
Type
IPR000719
Protein kinase domain
Domain
Domain
IPR011009
Protein kinase-like domain superfamily
Family
Homologous superfamily
IPR011029
Death-like domain superfamily
Family
Homologous superfamily
IPR017428
Interleukin-1 receptor-associated kinase 4
Family
Family
IPR037970
IRAK4, Death domain
Domain
Domain
Diseases
Show/Hide Table
Drugs
Show/Hide Table
Interactions
10 interactions
Interactor
Partner
Sources
Publications
Link
IRAK4_MOUSE
MYD88_MOUSE
BioGRID, DIP, IntAct
16306937
19378012
22011580
24529375
30108181
details
IRAK4_MOUSE
TIRAP_MOUSE
BioGRID
19378012
details
IRAK4_MOUSE
IRAK1_MOUSE
BioGRID
19378012
details
IRAK4_MOUSE
IRAK3_MOUSE
MINT
23376919
details
IRAK4_MOUSE
UBB_MOUSE
DIP
19815506
details
IRAK4_MOUSE
UBC_MOUSE
DIP
19815506
details
IRAK4_MOUSE
RS27A_MOUSE
DIP
19815506
details
IRAK4_MOUSE
RL40_MOUSE
DIP
19815506
details
IRAK4_MOUSE
IL1R1_MOUSE
BioGRID
15292196
17507369
details
IRAK4_MOUSE
TLR4_MOUSE
BioGRID
18772134
details
This website requires cookies in order to function. By using the site you are agreeing to this as outlined in our
Terms of Use
I Agree