Entity Details

Primary name SLAP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8R4L0
EntryNameSLAP2_MOUSE
FullNameSrc-like-adapter 2
TaxID10090
Evidenceevidence at protein level
Length259
SequenceStatuscomplete
DateCreated2003-04-23
DateModified2021-06-02

Ontological Relatives

GenesSla2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002250 adaptive immune response
GO:0005654 nucleoplasm
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0031410 cytoplasmic vesicle
GO:0035591 signaling adaptor activity
GO:0042110 T cell activation
GO:0043231 intracellular membrane-bounded organelle
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity
GO:0047485 protein N-terminus binding
GO:0050849 negative regulation of calcium-mediated signaling
GO:0050860 negative regulation of T cell receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Late endosome

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR035052 SLAP, SH2 domainDomainDomain
IPR035054 Src-like-adapter 2FamilyFamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions