Entity Details

Primary name SMYD2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8R5A0
EntryNameSMYD2_MOUSE
FullNameN-lysine methyltransferase SMYD2
TaxID10090
Evidenceevidence at protein level
Length433
SequenceStatuscomplete
DateCreated2004-05-10
DateModified2021-06-02

Ontological Relatives

GenesSmyd2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000993 RNA polymerase II complex binding
GO:0002039 p53 binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007507 heart development
GO:0008285 negative regulation of cell population proliferation
GO:0016279 protein-lysine N-methyltransferase activity
GO:0016571 histone methylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0018026 peptidyl-lysine monomethylation
GO:0018027 peptidyl-lysine dimethylation
GO:0034968 histone lysine methylation
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046872 metal ion binding
GO:0046975 histone methyltransferase activity (H3-K36 specific)

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR002893 Zinc finger, MYND-typeDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR044419 SMYD2, SET domainDomainDomain

Diseases

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Interactions

3 interactions