Entity Details

Primary name RPGF3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VCC8
EntryNameRPGF3_MOUSE
FullNameRap guanine nucleotide exchange factor 3
TaxID10090
Evidenceevidence at protein level
Length918
SequenceStatuscomplete
DateCreated2003-06-20
DateModified2021-06-02

Ontological Relatives

GenesRapgef3

GO terms

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GOName
GO:0001525 angiogenesis
GO:0014911 positive regulation of smooth muscle cell migration
GO:0030027 lamellipodium
GO:0030552 cAMP binding
GO:0045766 positive regulation of angiogenesis
GO:0045793 positive regulation of cell size
GO:0048471 perinuclear region of cytoplasm
GO:0051496 positive regulation of stress fiber assembly
GO:0060143 positive regulation of syncytium formation by plasma membrane fusion
GO:0071320 cellular response to cAMP
GO:0001934 positive regulation of protein phosphorylation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043025 neuronal cell body
GO:0043547 positive regulation of GTPase activity
GO:0043679 axon terminus
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046827 positive regulation of protein export from nucleus
GO:1904427 positive regulation of calcium ion transmembrane transport
GO:1990794 basolateral part of cell
GO:1990795 rod bipolar cell terminal bouton
GO:2000251 positive regulation of actin cytoskeleton reorganization
GO:0009925 basal plasma membrane
GO:0030175 filopodium
GO:0031090 organelle membrane
GO:0031526 brush border membrane
GO:0032966 negative regulation of collagen biosynthetic process
GO:0061028 establishment of endothelial barrier
GO:0071944 cell periphery
GO:1901985 positive regulation of protein acetylation
GO:1904426 positive regulation of GTP binding
GO:1904453 positive regulation of potassium:proton exchanging ATPase activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005902 microvillus
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0019904 protein domain specific binding
GO:0030426 growth cone
GO:0030864 cortical actin cytoskeleton
GO:0032486 Rap protein signal transduction
GO:0034242 negative regulation of syncytium formation by plasma membrane fusion
GO:0044325 transmembrane transporter binding
GO:0045177 apical part of cell
GO:0097470 ribbon synapse
GO:1990796 photoreceptor cell terminal bouton
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000591 DEP domainDomainDomain
IPR000595 Cyclic nucleotide-binding domainDomainDomain
IPR000651 Ras-like guanine nucleotide exchange factor, N-terminalDomainDomain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domainDomainDomain
IPR008937 Ras-like guanine nucleotide exchange factorFamilyFamily
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily
IPR018490 Cyclic nucleotide-binding-likeFamilyHomologous superfamily
IPR019804 Ras guanine-nucleotide exchange factor, conserved siteSiteConserved site
IPR023578 Ras guanine nucleotide exchange factor domain superfamilyFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
RPGF3_MOUSEARBK1_HUMANBioGRID20861385 details