Entity Details

Primary name MAVS_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VCF0
EntryNameMAVS_MOUSE
FullNameMitochondrial antiviral-signaling protein
TaxID10090
Evidenceevidence at protein level
Length503
SequenceStatuscomplete
DateCreated2005-11-08
DateModified2021-06-02

Ontological Relatives

GenesMavs

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0002735 positive regulation of myeloid dendritic cell cytokine production
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0007165 signal transduction
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0031966 mitochondrial membrane
GO:0032481 positive regulation of type I interferon production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035591 signaling adaptor activity
GO:0039529 RIG-I signaling pathway
GO:0042307 positive regulation of protein import into nucleus
GO:0042742 defense response to bacterium
GO:0045071 negative regulation of viral genome replication
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050700 CARD domain binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051607 defense response to virus
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:0060760 positive regulation of response to cytokine stimulus
GO:0071360 cellular response to exogenous dsRNA
GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production
GO:0071660 positive regulation of IP-10 production
GO:1900063 regulation of peroxisome organization

Subcellular Location

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Subcellular Location
Mitochondrion
Mitochondrion outer membrane
Peroxisome

Domains

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DomainNameCategoryType
IPR026148 Mitochondrial antiviral-signalling protein, metazoanFamilyFamily
IPR031964 Caspase recruitment domainDomainDomain
IPR042144 IPS1, CARD domainDomainDomain

Diseases

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