Entity Details

Primary name MUL1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VCM5
EntryNameMUL1_MOUSE
FullNameMitochondrial ubiquitin ligase activator of NFKB 1
TaxID10090
Evidenceevidence at protein level
Length352
SequenceStatuscomplete
DateCreated2007-02-20
DateModified2021-06-02

Ontological Relatives

GenesMul1

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0000266 mitochondrial fission
GO:0002039 p53 binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257 obsolete activation of JUN kinase activity
GO:0010637 negative regulation of mitochondrial fusion
GO:0010821 regulation of mitochondrion organization
GO:0016567 protein ubiquitination
GO:0019789 SUMO transferase activity
GO:0030308 negative regulation of cell growth
GO:0030424 axon
GO:0031307 integral component of mitochondrial outer membrane
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0031648 protein destabilization
GO:0033235 positive regulation of protein sumoylation
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045824 negative regulation of innate immune response
GO:0046872 metal ion binding
GO:0050689 negative regulation of defense response to virus by host
GO:0050821 protein stabilization
GO:0051646 mitochondrion localization
GO:0051881 regulation of mitochondrial membrane potential
GO:0051898 negative regulation of protein kinase B signaling
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0061630 ubiquitin protein ligase activity
GO:0071360 cellular response to exogenous dsRNA
GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production
GO:0090141 positive regulation of mitochondrial fission
GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1903861 positive regulation of dendrite extension
GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane
Peroxisome

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR022170 E3 Ubiquitin ligase MUL1-likeDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MUL1_MOUSENR6A1_MOUSEBioGRID18082624 details