Entity Details

Primary name CGL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VCN5
EntryNameCGL_MOUSE
FullNameCystathionine gamma-lyase
TaxID10090
Evidenceevidence at protein level
Length398
SequenceStatuscomplete
DateCreated2003-01-10
DateModified2021-06-02

Ontological Relatives

GenesCth

GO terms

Show/Hide Table
GOName
GO:0004121 cystathionine beta-lyase activity
GO:0004123 cystathionine gamma-lyase activity
GO:0005516 calmodulin binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006749 glutathione metabolic process
GO:0008285 negative regulation of cell population proliferation
GO:0016846 carbon-sulfur lyase activity
GO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
GO:0019343 cysteine biosynthetic process via cystathionine
GO:0019344 cysteine biosynthetic process
GO:0019346 transsulfuration
GO:0030170 pyridoxal phosphate binding
GO:0030308 negative regulation of cell growth
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044524 protein sulfhydration
GO:0044540 L-cystine L-cysteine-lyase (deaminating)
GO:0050667 homocysteine metabolic process
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051289 protein homotetramerization
GO:0070814 hydrogen sulfide biosynthetic process
GO:0080146 L-cysteine desulfhydrase activity
GO:1904831 positive regulation of aortic smooth muscle cell differentiation
GO:1990830 cellular response to leukemia inhibitory factor
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzymeFamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CGL_MOUSETOM20_MOUSEDIP22323590 details