Entity Details

Primary name UHRF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VDF2
EntryNameUHRF1_MOUSE
FullNameE3 ubiquitin-protein ligase UHRF1
TaxID10090
Evidenceevidence at protein level
Length782
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesUhrf1

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005886 plasma membrane
GO:0006281 DNA repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0008327 methyl-CpG binding
GO:0010216 maintenance of DNA methylation
GO:0010390 histone monoubiquitination
GO:0016363 nuclear matrix
GO:0016567 protein ubiquitination
GO:0016574 histone ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031493 nucleosomal histone binding
GO:0032270 positive regulation of cellular protein metabolic process
GO:0035064 methylated histone binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0044729 hemi-methylated DNA-binding
GO:0050678 regulation of epithelial cell proliferation
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003105 SRA-YDGDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015947 PUA-like superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR021991 UHRF1, tandem tudor domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036987 SRA-YDG superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table