Entity Details

Primary name AT1A1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VDN2
EntryNameAT1A1_MOUSE
FullNameSodium/potassium-transporting ATPase subunit alpha-1
TaxID10090
Evidenceevidence at protein level
Length1023
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesAtp1a1

GO terms

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GOName
GO:0002026 regulation of the force of heart contraction
GO:0002028 regulation of sodium ion transport
GO:0005391 P-type sodium:potassium-exchanging transporter activity
GO:0005524 ATP binding
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0005901 caveola
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0006883 cellular sodium ion homeostasis
GO:0008217 regulation of blood pressure
GO:0014069 postsynaptic density
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016791 phosphatase activity
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0030007 cellular potassium ion homeostasis
GO:0030315 T-tubule
GO:0030506 ankyrin binding
GO:0030955 potassium ion binding
GO:0031090 organelle membrane
GO:0031402 sodium ion binding
GO:0031947 negative regulation of glucocorticoid biosynthetic process
GO:0032991 protein-containing complex
GO:0036126 sperm flagellum
GO:0036376 sodium ion export across plasma membrane
GO:0042383 sarcolemma
GO:0042493 response to drug
GO:0043209 myelin sheath
GO:0043531 ADP binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0045121 membrane raft
GO:0045822 negative regulation of heart contraction
GO:0045823 positive regulation of heart contraction
GO:0045989 positive regulation of striated muscle contraction
GO:0046982 protein heterodimerization activity
GO:0051087 chaperone binding
GO:0055085 transmembrane transport
GO:0060081 membrane hyperpolarization
GO:0071260 cellular response to mechanical stimulus
GO:0071383 cellular response to steroid hormone stimulus
GO:0086004 regulation of cardiac muscle cell contraction
GO:0086009 membrane repolarization
GO:1902600 proton transmembrane transport
GO:1990239 steroid hormone binding
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane
Cell projection
Melanosome

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR004014 Cation-transporting P-type ATPase, N-terminalDomainDomain
IPR005775 P-type ATPase subfamily IIC, subunit alphaFamilyFamily
IPR006068 Cation-transporting P-type ATPase, C-terminalDomainDomain
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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