Entity Details

Primary name PER1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35973
EntryNamePER1_MOUSE
FullNamePeriod circadian protein homolog 1
TaxID10090
Evidenceevidence at protein level
Length1291
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPer1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001222 transcription corepressor binding
GO:0002028 regulation of sodium ion transport
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007623 circadian rhythm
GO:0008134 transcription factor binding
GO:0009416 response to light stimulus
GO:0010608 posttranscriptional regulation of gene expression
GO:0019900 kinase binding
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0032922 circadian regulation of gene expression
GO:0042634 regulation of hair cycle
GO:0042752 regulation of circadian rhythm
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043153 entrainment of circadian clock by photoperiod
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046329 negative regulation of JNK cascade
GO:0051591 response to cAMP
GO:0070888 E-box binding
GO:0070932 histone H3 deacetylation
GO:0097167 circadian regulation of translation
GO:1900015 regulation of cytokine production involved in inflammatory response
GO:1900744 regulation of p38MAPK cascade
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR013655 PAS fold-3DomainDomain
IPR022728 Period circadian-like, C-terminalDomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
PER1_MOUSETIM_MOUSEBioGRID, IntAct10231394 32325033 9856465 details
PER1_MOUSEKC1E_MOUSEBioGRID, DIP, IntAct21179498 21680841 21966515 23555304 details
PER1_MOUSECRY2_MOUSEBioGRID, DIP, IntAct14701732 23555304 24737000 details
PER1_MOUSECSK2B_HUMANIntAct23555304 details
PER1_MOUSEBHE40_HUMANIntAct23555304 details
PER1_MOUSECRY1_MOUSEBioGRID, DIP, IntAct14701732 21680841 21966515 23133559 23555304 24737000 25127877 details
PER1_MOUSEPER2_MOUSEBioGRID, DIP, IntAct, MINT14701732 20211142 23079727 24737000 32325033 details
PER1_MOUSEPER1_MOUSEBioGRID, DIP, IntAct20211142 21966515 24737000 details
PER1_MOUSEPER3_MOUSEBioGRID, DIP14701732 24737000 32325033 details
PER1_MOUSEFOXP1_MOUSEBioGRID, IntAct20211142 details
PER1_MOUSENFE2_MOUSEBioGRID, IntAct20211142 details
PER1_MOUSEEWS_MOUSEBioGRID, IntAct20211142 details
PER1_MOUSETLX3_MOUSEBioGRID, IntAct20211142 details
PER1_MOUSETIM_HUMANBioGRID9856465 details
PER1_MOUSEUBP2_MOUSEBioGRID21966515 23213472 details
PER1_MOUSEKC1A_MOUSEDIP21179498 details
PER1_MOUSEKC1D_MOUSEBioGRID, DIP21179498 21680841 details
PER1_MOUSEMK01_MOUSEDIP21179498 details
PER1_MOUSECIART_HUMANDIP24737000 details
PER1_MOUSECLOCK_MOUSEBioGRID14701732 16717091 21680841 32325033 details
PER1_MOUSEBMAL1_MOUSEBioGRID14701732 16717091 21680841 21966515 details
PER1_MOUSEHIF1A_HUMANBioGRID11726537 details
PER1_MOUSESIN3A_MOUSEBioGRID21680841 details
PER1_MOUSENONO_MOUSEBioGRID21680841 details
PER1_MOUSESFPQ_MOUSEBioGRID21680841 details