Entity Details

Primary name NTH_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35980
EntryNameNTH_MOUSE
FullNameEndonuclease III-like protein 1
TaxID10090
Evidenceevidence at transcript level
Length300
SequenceStatuscomplete
DateCreated2003-02-28
DateModified2021-06-02

Ontological Relatives

GenesNthl1

GO terms

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GOName
GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0006281 DNA repair
GO:0006285 base-excision repair, AP site formation
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0019104 DNA N-glycosylase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR000445 Helix-hairpin-helix motifSiteConserved site
IPR003265 HhH-GPD domainDomainDomain
IPR003651 Endonuclease III-like, iron-sulphur cluster loop motifSiteConserved site
IPR004036 Endonuclease III-like, conserved site-2SiteConserved site
IPR011257 DNA glycosylaseFamilyHomologous superfamily
IPR023170 Helix-hairpin-helix, base-excision DNA repair, C-terminalFamilyHomologous superfamily
IPR030841 Endonuclease III-like protein 1FamilyFamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink