Entity Details

Primary name GRK5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VEB1
EntryNameGRK5_MOUSE
FullNameG protein-coupled receptor kinase 5
TaxID10090
Evidenceevidence at protein level
Length590
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesGrk5

GO terms

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GOName
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0004674 protein serine/threonine kinase activity
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0007217 tachykinin receptor signaling pathway
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008289 lipid binding
GO:0016055 Wnt signaling pathway
GO:0016607 nuclear speck
GO:0031965 nuclear membrane
GO:0043066 negative regulation of apoptotic process
GO:0045444 fat cell differentiation
GO:0046777 protein autophosphorylation
GO:0047696 beta-adrenergic receptor kinase activity
GO:0051726 regulation of cell cycle
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000239 GPCR kinaseFamilyFamily
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR016137 RGS domainDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GRK5_MOUSEHDAC5_HUMANDIP18711143 details