Entity Details

Primary name RFA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VEE4
EntryNameRFA1_MOUSE
FullNameReplication protein A 70 kDa DNA-binding subunit
TaxID10090
Evidenceevidence at protein level
Length623
SequenceStatuscomplete
DateCreated2006-02-07
DateModified2021-06-02

Ontological Relatives

GenesRpa1

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000793 condensed chromosome
GO:0000794 condensed nuclear chromosome
GO:0000800 lateral element
GO:0001673 male germ cell nucleus
GO:0001701 in utero embryonic development
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005662 DNA replication factor A complex
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006289 nucleotide-excision repair
GO:0006298 mismatch repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007004 telomere maintenance via telomerase
GO:0008284 positive regulation of cell population proliferation
GO:0016605 PML body
GO:0030097 hemopoiesis
GO:0034502 protein localization to chromosome
GO:0043047 single-stranded telomeric DNA binding
GO:0046872 metal ion binding
GO:0048873 homeostasis of number of cells within a tissue
GO:0051276 chromosome organization
GO:0051321 meiotic cell cycle
GO:0090734 site of DNA damage
GO:0098505 G-rich strand telomeric DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-typeDomainDomain
IPR004591 Replication factor A protein 1FamilyFamily
IPR007199 Replication factor-A protein 1, N-terminalDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR013955 Replication factor A, C-terminalDomainDomain
IPR031657 Replication protein A, OB domainDomainDomain

Diseases

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Interactions

3 interactions