Entity Details

Primary name VPS4A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VEJ9
EntryNameVPS4A_MOUSE
FullNameVacuolar protein sorting-associated protein 4A
TaxID10090
Evidenceevidence at protein level
Length437
SequenceStatuscomplete
DateCreated2005-04-12
DateModified2021-06-02

Ontological Relatives

GenesVps4a

GO terms

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GOName
GO:0000922 spindle pole
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005774 vacuolar membrane
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006622 protein targeting to lysosome
GO:0006900 vesicle budding from membrane
GO:0006997 nucleus organization
GO:0007033 vacuole organization
GO:0007080 mitotic metaphase plate congression
GO:0008022 protein C-terminus binding
GO:0009838 abscission
GO:0010008 endosome membrane
GO:0016192 vesicle-mediated transport
GO:0016197 endosomal transport
GO:0016887 ATP hydrolysis activity
GO:0019076 viral release from host cell
GO:0019904 protein domain specific binding
GO:0030496 midbody
GO:0031267 small GTPase binding
GO:0031902 late endosome membrane
GO:0032367 intracellular cholesterol transport
GO:0032466 negative regulation of cytokinesis
GO:0032880 regulation of protein localization
GO:0034058 endosomal vesicle fusion
GO:0036258 multivesicular body assembly
GO:0039702 viral budding via host ESCRT complex
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0044877 protein-containing complex binding
GO:0044878 mitotic cytokinesis checkpoint signaling
GO:0048471 perinuclear region of cytoplasm
GO:0048524 positive regulation of viral process
GO:0051301 cell division
GO:0061738 late endosomal microautophagy
GO:0061952 midbody abscission
GO:0072319 vesicle uncoating
GO:0090543 Flemming body
GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
GO:1902188 positive regulation of viral release from host cell
GO:1903076 regulation of protein localization to plasma membrane
GO:1903543 positive regulation of exosomal secretion
GO:1903774 positive regulation of viral budding via host ESCRT complex
GO:1903902 positive regulation of viral life cycle

Subcellular Location

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Subcellular Location
Late endosome membrane
Midbody

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR007330 MIT domainDomainDomain
IPR015415 Vps4 oligomerisation, C-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031255 Vacuolar protein sorting-associated protein 4FamilyFamily
IPR036181 MIT domain superfamilyFamilyHomologous superfamily
IPR041569 AAA ATPase, AAA+ lid domainDomainDomain

Diseases

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Interactions

0 interactions

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