Entity Details

Primary name HNRPU_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VEK3
EntryNameHNRPU_MOUSE
FullNameHeterogeneous nuclear ribonucleoprotein U
TaxID10090
Evidenceevidence at protein level
Length800
SequenceStatuscomplete
DateCreated2009-11-03
DateModified2021-06-02

Ontological Relatives

GenesHnrnpu

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000228 nuclear chromosome
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000993 RNA polymerase II complex binding
GO:0001097 TFIIH-class transcription factor complex binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0003779 actin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005697 telomerase holoenzyme complex
GO:0005813 centrosome
GO:0006325 chromatin organization
GO:0006397 mRNA processing
GO:0007049 cell cycle
GO:0007346 regulation of mitotic cell cycle
GO:0008143 poly(A) binding
GO:0008380 RNA splicing
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0016071 mRNA metabolic process
GO:0016363 nuclear matrix
GO:0016607 nuclear speck
GO:0017069 snRNA binding
GO:0017130 poly(C) RNA binding
GO:0030496 midbody
GO:0031490 chromatin DNA binding
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032839 dendrite cytoplasm
GO:0032922 circadian regulation of gene expression
GO:0032991 protein-containing complex
GO:0033673 negative regulation of kinase activity
GO:0034046 poly(G) binding
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0036002 pre-mRNA binding
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042802 identical protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0043565 sequence-specific DNA binding
GO:0044877 protein-containing complex binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048255 mRNA stabilization
GO:0051301 cell division
GO:0051457 maintenance of protein location in nucleus
GO:0055013 cardiac muscle cell development
GO:0070034 telomerase RNA binding
GO:0070934 CRD-mediated mRNA stabilization
GO:0070937 CRD-mediated mRNA stability complex
GO:0071013 catalytic step 2 spliceosome
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071549 cellular response to dexamethasone stimulus
GO:0072686 mitotic spindle
GO:0090336 positive regulation of brown fat cell differentiation
GO:0090575 RNA polymerase II transcription regulator complex
GO:0098577 inactive sex chromosome
GO:0098963 dendritic transport of messenger ribonucleoprotein complex
GO:0099122 RNA polymerase II C-terminal domain binding
GO:1901673 regulation of mitotic spindle assembly
GO:1902275 regulation of chromatin organization
GO:1902425 positive regulation of attachment of mitotic spindle microtubules to kinetochore
GO:1902889 protein localization to spindle microtubule
GO:1990023 mitotic spindle midzone
GO:1990280 RNA localization to chromatin
GO:1990498 mitotic spindle microtubule
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:1990845 adaptive thermogenesis
GO:1990904 ribonucleoprotein complex
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
GO:2000648 positive regulation of stem cell proliferation
GO:2000737 negative regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Cell surface
Chromosome
Cytoplasm
Cytoplasmic granule
Midbody
Nucleus
Nucleus matrix
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001870 B30.2/SPRY domainDomainDomain
IPR003034 SAP domainDomainDomain
IPR003877 SPRY domainDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR026745 Heterogeneous nuclear ribonucleoprotein UFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035778 Heterogeneous nuclear ribonucleoprotein U, SPRY domainDomainDomain
IPR036361 SAP domain superfamilyFamilyHomologous superfamily
IPR043136 B30.2/SPRY domain superfamilyFamilyHomologous superfamily

Diseases

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