Entity Details

Primary name NKG2D_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO54709
EntryNameNKG2D_MOUSE
FullNameNKG2-D type II integral membrane protein
TaxID10090
Evidenceevidence at protein level
Length232
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesKlrk1

GO terms

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GOName
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002250 adaptive immune response
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0019900 kinase binding
GO:0030101 natural killer cell activation
GO:0030154 cell differentiation
GO:0030246 carbohydrate binding
GO:0030887 positive regulation of myeloid dendritic cell activation
GO:0032394 MHC class Ib receptor activity
GO:0032729 positive regulation of interferon-gamma production
GO:0038023 signaling receptor activity
GO:0042288 MHC class I protein binding
GO:0043065 positive regulation of apoptotic process
GO:0045087 innate immune response
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050830 defense response to Gram-positive bacterium
GO:0071222 cellular response to lipopolysaccharide

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR033992 Natural killer cell receptor-like, C-type lectin-like domainDomainDomain
IPR042169 NKG2-D type II integral membrane proteinFamilyFamily

Diseases

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Interactions

3 interactions