Entity Details

Primary name MRP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8VI47
EntryNameMRP2_MOUSE
FullNameATP-binding cassette sub-family C member 2
TaxID10090
Evidenceevidence at protein level
Length1543
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesAbcc2

GO terms

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GOName
GO:0005524 ATP binding
GO:0005887 integral component of plasma membrane
GO:0006855 drug transmembrane transport
GO:0006954 inflammatory response
GO:0006979 response to oxidative stress
GO:0007565 female pregnancy
GO:0008559 ABC-type xenobiotic transporter activity
GO:0009408 response to heat
GO:0009986 cell surface
GO:0010629 negative regulation of gene expression
GO:0015127 bilirubin transmembrane transporter activity
GO:0015431 ABC-type glutathione S-conjugate transporter activity
GO:0015694 mercury ion transport
GO:0015711 organic anion transport
GO:0015721 bile acid and bile salt transport
GO:0015722 canalicular bile acid transport
GO:0015732 prostaglandin transport
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0016999 antibiotic metabolic process
GO:0019904 protein domain specific binding
GO:0030644 cellular chloride ion homeostasis
GO:0031427 response to methotrexate
GO:0031526 brush border membrane
GO:0032355 response to estradiol
GO:0033762 response to glucagon
GO:0035690 cellular response to drug
GO:0038183 bile acid signaling pathway
GO:0042178 xenobiotic catabolic process
GO:0042493 response to drug
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042910 xenobiotic transmembrane transporter activity
GO:0043627 response to estrogen
GO:0046581 intercellular canaliculus
GO:0046618 drug export
GO:0046685 response to arsenic-containing substance
GO:0046691 intracellular canaliculus
GO:0050787 detoxification of mercury ion
GO:0055085 transmembrane transport
GO:0070327 thyroid hormone transport
GO:0070633 transepithelial transport
GO:0071222 cellular response to lipopolysaccharide
GO:0071347 cellular response to interleukin-1
GO:0071354 cellular response to interleukin-6
GO:0071356 cellular response to tumor necrosis factor
GO:0071549 cellular response to dexamethasone stimulus
GO:0071716 leukotriene transport
GO:0097327 response to antineoplastic agent
GO:0120188 regulation of bile acid secretion
GO:1901086 benzylpenicillin metabolic process
GO:1904486 response to 17alpha-ethynylestradiol
GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane
GO:1990962 xenobiotic transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR005292 Multi drug resistance-associated proteinFamilyFamily
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030247 ATP-binding cassette sub-family C member 2FamilyFamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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