Entity Details

Primary name S12A5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91V14
EntryNameS12A5_MOUSE
FullNameSolute carrier family 12 member 5
TaxID10090
Evidenceevidence at protein level
Length1138
SequenceStatuscomplete
DateCreated2002-12-13
DateModified2021-06-02

Ontological Relatives

GenesSlc12a5

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0006821 chloride transport
GO:0006873 cellular ion homeostasis
GO:0006884 cell volume homeostasis
GO:0006971 hypotonic response
GO:0007268 chemical synaptic transmission
GO:0007612 learning
GO:0008519 ammonium transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0015379 potassium:chloride symporter activity
GO:0015696 ammonium transport
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0030644 cellular chloride ion homeostasis
GO:0032590 dendrite membrane
GO:0035264 multicellular organism growth
GO:0040040 thermosensory behavior
GO:0042493 response to drug
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043198 dendritic shaft
GO:0043204 perikaryon
GO:0045202 synapse
GO:0051452 intracellular pH reduction
GO:0055064 chloride ion homeostasis
GO:0055075 potassium ion homeostasis
GO:0060996 dendritic spine development
GO:0071944 cell periphery
GO:1902476 chloride transmembrane transport
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000076 K/Cl co-transporterFamilyFamily
IPR004841 Amino acid permease/ SLC12A domainDomainDomain
IPR004842 SLC12A transporter familyFamilyFamily
IPR018491 SLC12A transporter, C-terminalDomainDomain
IPR030358 K/Cl co-transporter 2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01216 FinasterideDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink