Entity Details

Primary name IF4A3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91VC3
EntryNameIF4A3_MOUSE
FullNameEukaryotic initiation factor 4A-III
TaxID10090
Evidenceevidence at protein level
Length411
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GenesEif4a3

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003729 mRNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006364 rRNA processing
GO:0008143 poly(A) binding
GO:0010629 negative regulation of gene expression
GO:0016607 nuclear speck
GO:0017148 negative regulation of translation
GO:0030425 dendrite
GO:0035145 exon-exon junction complex
GO:0035368 selenocysteine insertion sequence binding
GO:0035613 RNA stem-loop binding
GO:0043021 ribonucleoprotein complex binding
GO:0043025 neuronal cell body
GO:0045182 translation regulator activity
GO:0045727 positive regulation of translation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0051028 mRNA transport
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:0090394 negative regulation of excitatory postsynaptic potential
GO:0098978 glutamatergic synapse
GO:0099524 postsynaptic cytosol
GO:0099578 regulation of translation at postsynapse, modulating synaptic transmission
GO:1902415 regulation of mRNA binding
GO:1904570 negative regulation of selenocysteine incorporation
GO:1904574 negative regulation of selenocysteine insertion sequence binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000629 ATP-dependent RNA helicase DEAD-box, conserved siteSiteConserved site
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IF4A3_MOUSEOTUD4_HUMANBioGRID31138677 details