Entity Details

Primary name Braf
Entity type gene
Source Source Link

Details

PrimaryID109880
RefseqGene
SymbolBraf
NameBraf transforming gene
Chromosome6
Location6 18.43 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-08-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsBRAF_MOUSE

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0002318 myeloid progenitor cell differentiation
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0008542 visual learning
GO:0010628 positive regulation of gene expression
GO:0010764 negative regulation of fibroblast migration
GO:0010828 positive regulation of glucose transmembrane transport
GO:0016020 membrane
GO:0030154 cell differentiation
GO:0030878 thyroid gland development
GO:0031267 small GTPase binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035019 somatic stem cell population maintenance
GO:0035690 cellular response to drug
GO:0042127 regulation of cell population proliferation
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043367 CD4-positive, alpha-beta T cell differentiation
GO:0043368 positive T cell selection
GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0043434 response to peptide hormone
GO:0043524 negative regulation of neuron apoptotic process
GO:0044297 cell body
GO:0044877 protein-containing complex binding
GO:0045580 regulation of T cell differentiation
GO:0046632 alpha-beta T cell differentiation
GO:0048538 thymus development
GO:0048679 regulation of axon regeneration
GO:0048680 positive regulation of axon regeneration
GO:0050772 positive regulation of axonogenesis
GO:0050852 T cell receptor signaling pathway
GO:0051496 positive regulation of stress fiber assembly
GO:0051591 response to cAMP
GO:0060291 long-term synaptic potentiation
GO:0060323 head morphogenesis
GO:0060324 face development
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070413 trehalose metabolism in response to stress
GO:0071277 cellular response to calcium ion
GO:0090150 establishment of protein localization to membrane
GO:0097110 scaffold protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1990090 cellular response to nerve growth factor stimulus
GO:2000301 negative regulation of synaptic vesicle exocytosis
GO:2000352 negative regulation of endothelial cell apoptotic process

Diseases

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Interactions

71 interactions

InteractorPartnerSourcesPublicationsLink
BrafYwhahBioGRID, MINT27034005 8668348 details
BrafHrasBioGRID, MINT27034005 8668348 details
BrafMap2k1BioGRID, MINT27034005 8668348 details
BrafMap2k2BioGRID, MINT27034005 8668348 details
BrafYwhazBioGRID16959763 27034005 8668348 details
BrafYwhaqBioGRID27034005 8668348 details
BrafRaf1BioGRID, IntAct18332145 20141835 22169110 27034005 details
BrafNRASDIP21478863 details
BrafYWHAZIntAct16959763 details
BrafRab38IntAct26885862 details
BrafEedBioGRID24457600 details
BrafFancd2BioGRID28378742 details
BrafAkap8BioGRID27034005 details
BrafHsp90b1BioGRID27034005 details
BrafCsnk2bBioGRID27034005 details
BrafHspa8BioGRID27034005 details
BrafPhb2BioGRID27034005 details
BrafAnxa2BioGRID27034005 details
BrafG3bp2BioGRID27034005 details
BrafCdk1BioGRID27034005 details
BrafAnxa5BioGRID27034005 details
BrafHspa9BioGRID27034005 details
BrafSnx9BioGRID27034005 details
BrafPhbBioGRID27034005 details
BrafVimBioGRID27034005 details
BrafSfnBioGRID27034005 details
BrafPgam1BioGRID27034005 details
BrafDnaja1BioGRID27034005 details
BrafIqgap1BioGRID27034005 details
BrafYwhabBioGRID27034005 details
BrafYwhaeBioGRID27034005 details
BrafGnai2BioGRID27034005 details
BrafYwhagBioGRID27034005 details
BrafCdc37BioGRID27034005 details
BrafHsp90aa1BioGRID27034005 details
BrafNpm1BioGRID27034005 details
BrafWdr26BioGRID27034005 details
BrafMcm3BioGRID27034005 details
BrafGpi1BioGRID27034005 details
BrafDock1BioGRID27034005 details
BrafEif5BioGRID27034005 details
BrafPi4kaBioGRID27034005 details
BrafGramd4BioGRID27034005 details
BrafEcpasBioGRID27034005 details
BrafGnai3BioGRID27034005 details
BrafCdk2BioGRID27034005 details
BrafArafBioGRID27034005 details
BrafDnajb12BioGRID27034005 details
BrafPpp1r10BioGRID27034005 details
BrafFmnl3BioGRID27034005 details
BrafMc1rBioGRID27034005 details
BrafSgpl1BioGRID27034005 details
BrafHsd11b2BioGRID27034005 details
BrafDnajb11BioGRID27034005 details
BrafPld2BioGRID27034005 details
BrafRap1bBioGRID27034005 details
BrafWdr6BioGRID27034005 details
BrafCpne3BioGRID27034005 details
BrafMyofBioGRID27034005 details
BrafCopaBioGRID27034005 details
BrafUblcp1BioGRID27034005 details
BrafPpp1caBioGRID27034005 details
BrafPip4k2cBioGRID27034005 details
BrafGnasBioGRID27034005 details
BrafPpp2cbBioGRID27034005 details
BrafHspa5BioGRID27034005 details
BrafRanBioGRID27034005 details
BrafAtad3aBioGRID27034005 details
BrafUsp7BioGRID27034005 details
BrafBrapBioGRID32325033 details
BrafPhkbBioGRID32325033 details