Entity Details

Primary name Grk2
Entity type gene
Source Source Link

Details

PrimaryID110355
RefseqGene
SymbolGrk2
NameG protein-coupled receptor kinase 2
Chromosome19
Location19 3.98 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-08-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsARBK1_MOUSE

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0002026 regulation of the force of heart contraction
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0003108 negative regulation of the force of heart contraction by chemical signal
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005901 caveola
GO:0005929 cilium
GO:0006468 protein phosphorylation
GO:0006979 response to oxidative stress
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007217 tachykinin receptor signaling pathway
GO:0007507 heart development
GO:0010661 positive regulation of muscle cell apoptotic process
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019079 viral genome replication
GO:0030424 axon
GO:0031623 receptor internalization
GO:0031625 ubiquitin protein ligase binding
GO:0031755 Edg-2 lysophosphatidic acid receptor binding
GO:0031850 delta-type opioid receptor binding
GO:0031851 kappa-type opioid receptor binding
GO:0032755 positive regulation of interleukin-6 production
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0033605 positive regulation of catecholamine secretion
GO:0042311 vasodilation
GO:0042699 follicle-stimulating hormone signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0045907 positive regulation of vasoconstriction
GO:0045988 negative regulation of striated muscle contraction
GO:0046325 negative regulation of glucose import
GO:0046718 viral entry into host cell
GO:0047696 beta-adrenergic receptor kinase activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0048709 oligodendrocyte differentiation
GO:0051457 maintenance of protein location in nucleus
GO:0060048 cardiac muscle contraction
GO:0071333 cellular response to glucose stimulus
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0097110 scaffold protein binding
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:1900077 negative regulation of cellular response to insulin stimulus
GO:1901081 negative regulation of relaxation of smooth muscle
GO:1904058 positive regulation of sensory perception of pain
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1990869 cellular response to chemokine
GO:2000117 negative regulation of cysteine-type endopeptidase activity
GO:2000463 positive regulation of excitatory postsynaptic potential

Diseases

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