Entity Details

Primary name Egln1
Entity type gene
Source Source Link

Details

PrimaryID112405
RefseqGene
SymbolEgln1
Nameegl-9 family hypoxia-inducible factor 1
Chromosome8
Location8
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-08-22
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsEGLN1_MOUSE

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006879 cellular iron ion homeostasis
GO:0008198 ferrous iron binding
GO:0014069 postsynaptic density
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019899 enzyme binding
GO:0031418 L-ascorbic acid binding
GO:0031543 peptidyl-proline dioxygenase activity
GO:0031545 peptidyl-proline 4-dioxygenase activity
GO:0032364 oxygen homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045765 regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity
GO:0055008 cardiac muscle tissue morphogenesis
GO:0060347 heart trabecula formation
GO:0060412 ventricular septum morphogenesis
GO:0060711 labyrinthine layer development
GO:0071456 cellular response to hypoxia
GO:0071731 response to nitric oxide
GO:0098978 glutamatergic synapse
GO:0099175 regulation of postsynapse organization
GO:0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission
GO:1901214 regulation of neuron death
GO:1901216 positive regulation of neuron death
GO:1905290 negative regulation of CAMKK-AMPK signaling cascade

Diseases

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Interactions

6 interactions