Entity Details

Primary name Spred2
Entity type gene
Source Source Link

Details

PrimaryID114716
RefseqGene
SymbolSpred2
Namesprouty-related EVH1 domain containing 2
Chromosome11
Location11
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-09-21
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSPRE2_MOUSE

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0005173 stem cell factor receptor binding
GO:0005886 plasma membrane
GO:0007275 multicellular organism development
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0030291 protein serine/threonine kinase inhibitor activity
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030658 transport vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0090311 regulation of protein deacetylation
GO:1902747 negative regulation of lens fiber cell differentiation

Diseases

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Interactions

23 interactions

InteractorPartnerSourcesPublicationsLink
Spred2NF1IntAct26635368 details
Spred2NBR1BioGRID19822672 details
Spred2CTSZBioGRID, IntAct26496610 details
Spred2PDE3ABioGRID, IntAct26496610 details
Spred2FXR1BioGRID, IntAct26496610 details
Spred2BIN3BioGRID, IntAct26496610 details
Spred2NKTRBioGRID, IntAct26496610 details
Spred2MYCBP2BioGRID, IntAct26496610 details
Spred2KLHL7BioGRID, IntAct26496610 details
Spred2TAX1BP1BioGRID, IntAct26496610 details
Spred2PSRC1BioGRID, IntAct26496610 details
Spred2ANKRD16BioGRID, IntAct26496610 details
Spred2SRSF9BioGRID, IntAct26496610 details
Spred2PNNBioGRID, IntAct26496610 details
Spred2TARS3BioGRID, IntAct26496610 details
Spred2PRDX3BioGRID, IntAct26496610 details
Spred2TXNL4ABioGRID, IntAct26496610 details
Spred2B4GALT1BioGRID, IntAct26496610 details
Spred2ZBTB48BioGRID26496610 details
Spred2SRSF1BioGRID26496610 details
Spred2KitBioGRID32325033 details
Spred2Tesk1BioGRID32325033 details
Spred2Top3bBioGRID32325033 details