Entity Details

Primary name Acvrl1
Entity type gene
Source Source Link

Details

PrimaryID11482
RefseqGene
SymbolAcvrl1
Nameactivin A receptor, type II-like 1
Chromosome15
Location15
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsACVL1_MOUSE

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0001701 in utero embryonic development
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0001946 lymphangiogenesis
GO:0001974 blood vessel remodeling
GO:0003203 endocardial cushion morphogenesis
GO:0004674 protein serine/threonine kinase activity
GO:0005024 transforming growth factor beta-activated receptor activity
GO:0005025 transforming growth factor beta receptor activity, type I
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007162 negative regulation of cell adhesion
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007507 heart development
GO:0008015 blood circulation
GO:0008217 regulation of blood pressure
GO:0008285 negative regulation of cell population proliferation
GO:0009953 dorsal/ventral pattern formation
GO:0009986 cell surface
GO:0010596 negative regulation of endothelial cell migration
GO:0010629 negative regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016361 activin receptor activity, type I
GO:0019901 protein kinase binding
GO:0030308 negative regulation of cell growth
GO:0030336 negative regulation of cell migration
GO:0030425 dendrite
GO:0030509 BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0035313 wound healing, spreading of epidermal cells
GO:0035912 dorsal aorta morphogenesis
GO:0042118 endothelial cell activation
GO:0043025 neuronal cell body
GO:0043235 receptor complex
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0045602 negative regulation of endothelial cell differentiation
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0048185 activin binding
GO:0048514 blood vessel morphogenesis
GO:0050431 transforming growth factor beta binding
GO:0051895 negative regulation of focal adhesion assembly
GO:0060836 lymphatic endothelial cell differentiation
GO:0060840 artery development
GO:0060841 venous blood vessel development
GO:0061154 endothelial tube morphogenesis
GO:0061298 retina vasculature development in camera-type eye
GO:0070724 BMP receptor complex
GO:0071363 cellular response to growth factor stimulus
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071773 cellular response to BMP stimulus
GO:0098821 BMP receptor activity
GO:2000279 negative regulation of DNA biosynthetic process

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
Acvrl1Cdh5MINT18337748 details
Acvrl1EngMINT18337748 details
Acvrl1Tgfbr2MINT18337748 details
Acvrl1Tgfbr1BioGRID14580334 details