Entity Details

Primary name POTE1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91WC1
EntryNamePOTE1_MOUSE
FullNameProtection of telomeres protein 1
TaxID10090
Evidenceevidence at protein level
Length640
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesPot1a

GO terms

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GOName
GO:0000781 chromosome, telomeric region
GO:0000783 nuclear telomere cap complex
GO:0005654 nucleoplasm
GO:0007004 telomere maintenance via telomerase
GO:0010521 telomerase inhibitor activity
GO:0016233 telomere capping
GO:0017151 DEAD/H-box RNA helicase binding
GO:0032202 telomere assembly
GO:0032210 regulation of telomere maintenance via telomerase
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032508 DNA duplex unwinding
GO:0042162 telomeric DNA binding
GO:0043047 single-stranded telomeric DNA binding
GO:0051096 positive regulation of helicase activity
GO:0051276 chromosome organization
GO:0051973 positive regulation of telomerase activity
GO:0051974 negative regulation of telomerase activity
GO:0060383 positive regulation of DNA strand elongation
GO:0061820 telomeric D-loop disassembly
GO:0061821 telomeric D-loop binding
GO:0070187 shelterin complex
GO:0070200 establishment of protein localization to telomere
GO:0098505 G-rich strand telomeric DNA binding
GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding
GO:1905774 regulation of DNA helicase activity
GO:1905776 positive regulation of DNA helicase activity
GO:1990955 G-rich single-stranded DNA binding
GO:2001032 regulation of double-strand break repair via nonhomologous end joining

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR011564 Telomeric single stranded DNA binding POT1/Cdc13DomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR028389 Protection of telomeres protein 1FamilyFamily
IPR032042 Protection of telomeres protein 1, ssDNA-binding domainDomainDomain

Diseases

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