Entity Details

Primary name Alox5
Entity type gene
Source Source Link

Details

PrimaryID11689
RefseqGene
SymbolAlox5
Namearachidonate 5-lipoxygenase
Chromosome6
Location6 53.79 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsLOX5_MOUSE

GO terms

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GOName
GO:0001937 negative regulation of endothelial cell proliferation
GO:0002232 leukocyte chemotaxis involved in inflammatory response
GO:0002523 leukocyte migration involved in inflammatory response
GO:0002526 acute inflammatory response
GO:0002540 leukotriene production involved in inflammatory response
GO:0004051 arachidonate 5-lipoxygenase activity
GO:0004052 arachidonate 12(S)-lipoxygenase activity
GO:0005506 iron ion binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005641 nuclear envelope lumen
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006691 leukotriene metabolic process
GO:0006954 inflammatory response
GO:0006959 humoral immune response
GO:0016363 nuclear matrix
GO:0016525 negative regulation of angiogenesis
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016787 hydrolase activity
GO:0019233 sensory perception of pain
GO:0019369 arachidonic acid metabolic process
GO:0019370 leukotriene biosynthetic process
GO:0019372 lipoxygenase pathway
GO:0030425 dendrite
GO:0030501 positive regulation of bone mineralization
GO:0031965 nuclear membrane
GO:0034440 lipid oxidation
GO:0036336 dendritic cell migration
GO:0036403 arachidonate 8(S)-lipoxygenase activity
GO:0042383 sarcolemma
GO:0042593 glucose homeostasis
GO:0043651 linoleic acid metabolic process
GO:0045598 regulation of fat cell differentiation
GO:0045907 positive regulation of vasoconstriction
GO:0048471 perinuclear region of cytoplasm
GO:0050727 regulation of inflammatory response
GO:0050728 negative regulation of inflammatory response
GO:0050796 regulation of insulin secretion
GO:0051122 hepoxilin biosynthetic process
GO:0061044 negative regulation of vascular wound healing
GO:0061045 negative regulation of wound healing
GO:0106014 regulation of inflammatory response to wounding
GO:1900015 regulation of cytokine production involved in inflammatory response
GO:1900407 regulation of cellular response to oxidative stress
GO:1901753 leukotriene A4 biosynthetic process
GO:1903426 regulation of reactive oxygen species biosynthetic process
GO:1903573 negative regulation of response to endoplasmic reticulum stress
GO:1903671 negative regulation of sprouting angiogenesis
GO:1904960 positive regulation of cytochrome-c oxidase activity
GO:1904999 positive regulation of leukocyte adhesion to arterial endothelial cell
GO:2001301 lipoxin biosynthetic process

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
Alox5Alox5apBioGRID19075240 details
Alox5GsapBioGRID26076991 details
Alox5Camk2gBioGRID32325033 details
Alox5Hhipl2BioGRID32325033 details