Entity Details

Primary name Apaf1
Entity type gene
Source Source Link

Details

PrimaryID11783
RefseqGene
SymbolApaf1
Nameapoptotic peptidase activating factor 1
Chromosome10
Location10 45.47 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsAPAF_MOUSE

GO terms

Show/Hide Table
GOName
GO:0001666 response to hypoxia
GO:0001822 kidney development
GO:0001843 neural tube closure
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275 multicellular organism development
GO:0007420 brain development
GO:0007568 aging
GO:0007584 response to nutrient
GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010659 cardiac muscle cell apoptotic process
GO:0030154 cell differentiation
GO:0030900 forebrain development
GO:0031072 heat shock protein binding
GO:0032991 protein-containing complex
GO:0042802 identical protein binding
GO:0043293 apoptosome
GO:0043531 ADP binding
GO:0051402 neuron apoptotic process
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1902510 regulation of apoptotic DNA fragmentation
GO:2001235 positive regulation of apoptotic signaling pathway

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
Apaf1Ppp1caBioGRID, IntAct17274640 details
Apaf1Casp8BioGRID32325033 details
Apaf1Tnfrsf23BioGRID32325033 details