Entity Details

Primary name Axin1
Entity type gene
Source Source Link

Details

PrimaryID12005
RefseqGene
SymbolAxin1
Nameaxin 1
Chromosome17
Location17 13.07 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsAXIN1_MOUSE

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0001701 in utero embryonic development
GO:0001932 regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0002039 p53 binding
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0006913 nucleocytoplasmic transport
GO:0006915 apoptotic process
GO:0007605 sensory perception of sound
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0009950 dorsal/ventral axis specification
GO:0009953 dorsal/ventral pattern formation
GO:0010629 negative regulation of gene expression
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0014069 postsynaptic density
GO:0015630 microtubule cytoskeleton
GO:0016055 Wnt signaling pathway
GO:0016328 lateral plasma membrane
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0030159 signaling receptor complex adaptor activity
GO:0030163 protein catabolic process
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030877 beta-catenin destruction complex
GO:0031122 cytoplasmic microtubule organization
GO:0031398 positive regulation of protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031625 ubiquitin protein ligase binding
GO:0032147 activation of protein kinase activity
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032991 protein-containing complex
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0034622 cellular protein-containing complex assembly
GO:0036342 post-anal tail morphogenesis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043507 positive regulation of JUN kinase activity
GO:0043621 protein self-association
GO:0045599 negative regulation of fat cell differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0045860 positive regulation of protein kinase activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046330 positive regulation of JNK cascade
GO:0046332 SMAD binding
GO:0048318 axial mesoderm development
GO:0048320 axial mesoderm formation
GO:0048471 perinuclear region of cytoplasm
GO:0051248 negative regulation of protein metabolic process
GO:0051443 positive regulation of ubiquitin-protein transferase activity
GO:0060070 canonical Wnt signaling pathway
GO:0060090 molecular adaptor activity
GO:0060322 head development
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0070016 armadillo repeat domain binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0071514 genetic imprinting
GO:0071944 cell periphery
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1990909 Wnt signalosome
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
Axin1Rnf111BioGRID, MINT16601693 details
Axin1GSK3ABioGRID, IntAct20368287 details
Axin1GSK3Bbhf-ucl, BioGRID, IntAct10330403 12421363 20368287 22682247 details
Axin1TNKSDIP19759537 details
Axin1Gsk3bbhf-ucl, BioGRID, MINT10318824 14734535 18316368 19107203 19581931 21242974 22682247 25331900 details
Axin1Lrp5BioGRID, MINT11336703 19075000 19581931 details
Axin1Ctnnb1BioGRID, IntAct, UniProt10318824 12805222 17053159 18316368 21242974 22682247 24976009 25873176 details
Axin1APC2BioGRID10330403 details
Axin1Axin1BioGRID12223491 15579909 18316368 9920888 details
Axin1Ppp2caBioGRID9920888 details
Axin1Map3k4BioGRID12878610 18316368 details
Axin1Kif3aBioGRID22473005 details
Axin1Nck2BioGRID11557983 details
Axin1Prmt1BioGRID21242974 details
Axin1Pias1BioGRID12223491 details
Axin1Pias2BioGRID12223491 details
Axin1Pias4BioGRID12223491 details
Axin1Smad3BioGRID, MINT16601693 details
Axin1Smad7BioGRID, MINT16601693 details
Axin1Smad6BioGRID, MINT16601693 details
Axin1CTNNB1bhf-ucl, BioGRID, DIP, MINT10330403 12421363 18509060 20531388 details
Axin1Dab2MINT, UniProt12805222 19581931 details
Axin1Ppp1caMINT19581931 details
Axin1Dvl3UniProt12805222 details
Axin1LRP6bhf-ucl12897152 19107203 details
Axin1AidaMINT25117763 details
Axin1Wwtr1IntAct24976009 details
Axin1YAP1IntAct24976009 details
Axin1TGIF1IntAct25873176 details
Axin1UbbDIP18509060 details
Axin1UbcDIP18509060 details
Axin1Rps27aDIP18509060 details
Axin1Uba52DIP18509060 details
Axin1Cdh2BioGRID19075000 details
Axin1Rnf11BioGRID16601693 details
Axin1Ppp2r1aBioGRID9920888 details
Axin1Dixdc1BioGRID15579909 details
Axin1Dvl2BioGRID15579909 details
Axin1Cops2BioGRID19576224 details
Axin1Trp53BioGRID15526030 details
Axin1Hipk2BioGRID15526030 details
Axin1Map2k1BioGRID12223491 18316368 details
Axin1AMMECR1MINT21304492 details
Axin1TNKS2DIP19759537 details
Axin1Lrp6IntAct22682247 24976009 details
Axin1Lrrk2BioGRID, IntAct22899650 details
Axin1Yap1IntAct24976009 details
Axin1Xpo1IntAct25873176 details
Axin1CfdBioGRID30550785 details
Axin1Fndc5BioGRID30550785 details