Entity Details

Primary name Blm
Entity type gene
Source Source Link

Details

PrimaryID12144
RefseqGene
SymbolBlm
NameBloom syndrome, RecQ like helicase
Chromosome7
Location7 45.65 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsBLM_MOUSE

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000228 nuclear chromosome
GO:0000400 four-way junction DNA binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000729 DNA double-strand break processing
GO:0000781 chromosome, telomeric region
GO:0000800 lateral element
GO:0001673 male germ cell nucleus
GO:0002039 p53 binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 cellular response to DNA damage stimulus
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0008094 ATPase, acting on DNA
GO:0008270 zinc ion binding
GO:0009378 four-way junction helicase activity
GO:0010165 response to X-ray
GO:0016363 nuclear matrix
GO:0016605 PML body
GO:0016887 ATP hydrolysis activity
GO:0031297 replication fork processing
GO:0032508 DNA duplex unwinding
GO:0032991 protein-containing complex
GO:0035690 cellular response to drug
GO:0036310 ATP-dependent DNA/DNA annealing activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0044806 G-quadruplex DNA unwinding
GO:0045120 pronucleus
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045910 negative regulation of DNA recombination
GO:0045950 negative regulation of mitotic recombination
GO:0046632 alpha-beta T cell differentiation
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0051098 regulation of binding
GO:0051259 protein complex oligomerization
GO:0051260 protein homooligomerization
GO:0051276 chromosome organization
GO:0051782 negative regulation of cell division
GO:0051880 G-quadruplex DNA binding
GO:0061749 forked DNA-dependent helicase activity
GO:0061820 telomeric D-loop disassembly
GO:0061821 telomeric D-loop binding
GO:0070244 negative regulation of thymocyte apoptotic process
GO:0071479 cellular response to ionizing radiation
GO:0072711 cellular response to hydroxyurea
GO:0072757 cellular response to camptothecin
GO:0090329 regulation of DNA-dependent DNA replication
GO:1905168 positive regulation of double-strand break repair via homologous recombination
GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding
GO:1990414 replication-born double-strand break repair via sister chromatid exchange

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
BlmTfe3BioGRID30595499 details
BlmAtmBioGRID32325033 details
BlmFancd2BioGRID32325033 details
BlmMsh6BioGRID32325033 details
BlmNbnBioGRID32325033 details
BlmRfc1BioGRID32325033 details
BlmTopbp1BioGRID32325033 details