Entity Details

Primary name WWOX_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91WL8
EntryNameWWOX_MOUSE
FullNameWW domain-containing oxidoreductase
TaxID10090
Evidenceevidence at protein level
Length414
SequenceStatuscomplete
DateCreated2005-11-22
DateModified2021-06-02

Ontological Relatives

GenesWwox

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0016055 Wnt signaling pathway
GO:0016491 oxidoreductase activity
GO:0019899 enzyme binding
GO:0030178 negative regulation of Wnt signaling pathway
GO:0042802 identical protein binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048705 skeletal system morphogenesis
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097191 extrinsic apoptotic signaling pathway
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR001202 WW domainDomainDomain
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR036020 WW domain superfamilyFamilyHomologous superfamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR042732 WWOX, classical (c)-like SDR domainDomainDomain

Diseases

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Interactions

4 interactions