Entity Details

Primary name Casp4
Entity type gene
Source Source Link

Details

PrimaryID12363
RefseqGene
SymbolCasp4
Namecaspase 4, apoptosis-related cysteine peptidase
Chromosome9
Location9 2.46 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCASP4_MOUSE

GO terms

Show/Hide Table
GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007015 actin filament organization
GO:0016540 protein autoprocessing
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032991 protein-containing complex
GO:0035234 ectopic germ cell programmed cell death
GO:0042981 regulation of apoptotic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045087 innate immune response
GO:0050700 CARD domain binding
GO:0050727 regulation of inflammatory response
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070269 pyroptosis
GO:0072557 IPAF inflammasome complex
GO:0072559 NLRP3 inflammasome complex
GO:0097110 scaffold protein binding
GO:0097169 AIM2 inflammasome complex
GO:0097193 intrinsic apoptotic signaling pathway
GO:0097194 execution phase of apoptosis
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway
GO:1904646 cellular response to amyloid-beta

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
Casp4GSDMDDIP26375003 details
Casp4GsdmdDIP26375259 details