Entity Details

Primary name Ctnnb1
Entity type gene
Source Source Link

Details

PrimaryID12387
RefseqGene
SymbolCtnnb1
Namecatenin (cadherin associated protein), beta 1
Chromosome9
Location9 72.19 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCTNB1_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000209 protein polyubiquitination
GO:0000578 embryonic axis specification
GO:0000791 euchromatin
GO:0000904 cell morphogenesis involved in differentiation
GO:0000922 spindle pole
GO:0001221 transcription coregulator binding
GO:0001501 skeletal system development
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001570 vasculogenesis
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001701 in utero embryonic development
GO:0001702 gastrulation with mouth forming second
GO:0001706 endoderm formation
GO:0001708 cell fate specification
GO:0001709 cell fate determination
GO:0001711 endodermal cell fate commitment
GO:0001764 neuron migration
GO:0001822 kidney development
GO:0001840 neural plate development
GO:0001894 tissue homeostasis
GO:0001944 vasculature development
GO:0002052 positive regulation of neuroblast proliferation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002089 lens morphogenesis in camera-type eye
GO:0003223 ventricular compact myocardium morphogenesis
GO:0003266 regulation of secondary heart field cardioblast proliferation
GO:0003338 metanephros morphogenesis
GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005916 fascia adherens
GO:0005923 bicellular tight junction
GO:0005938 cell cortex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007268 chemical synaptic transmission
GO:0007398 ectoderm development
GO:0007403 glial cell fate determination
GO:0007507 heart development
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009948 anterior/posterior axis specification
GO:0009950 dorsal/ventral axis specification
GO:0009953 dorsal/ventral pattern formation
GO:0009954 proximal/distal pattern formation
GO:0009987 cellular process
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0014010 Schwann cell proliferation
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0016331 morphogenesis of embryonic epithelium
GO:0016342 catenin complex
GO:0016525 negative regulation of angiogenesis
GO:0016600 flotillin complex
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0021819 layer formation in cerebral cortex
GO:0022009 central nervous system vasculogenesis
GO:0022405 hair cycle process
GO:0030018 Z disc
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030097 hemopoiesis
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030217 T cell differentiation
GO:0030316 osteoclast differentiation
GO:0030324 lung development
GO:0030331 estrogen receptor binding
GO:0030539 male genitalia development
GO:0030856 regulation of epithelial cell differentiation
GO:0030858 positive regulation of epithelial cell differentiation
GO:0030877 beta-catenin destruction complex
GO:0030900 forebrain development
GO:0030901 midbrain development
GO:0030902 hindbrain development
GO:0030997 regulation of centriole-centriole cohesion
GO:0031016 pancreas development
GO:0031069 hair follicle morphogenesis
GO:0031253 cell projection membrane
GO:0031528 microvillus membrane
GO:0031641 regulation of myelination
GO:0031965 nuclear membrane
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032331 negative regulation of chondrocyte differentiation
GO:0032355 response to estradiol
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0032991 protein-containing complex
GO:0032993 protein-DNA complex
GO:0033077 T cell differentiation in thymus
GO:0033234 negative regulation of protein sumoylation
GO:0034097 response to cytokine
GO:0034332 adherens junction organization
GO:0034333 adherens junction assembly
GO:0034394 protein localization to cell surface
GO:0034613 cellular protein localization
GO:0034750 Scrib-APC-beta-catenin complex
GO:0035050 embryonic heart tube development
GO:0035112 genitalia morphogenesis
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0035255 ionotropic glutamate receptor binding
GO:0036023 embryonic skeletal limb joint morphogenesis
GO:0036520 astrocyte-dopaminergic neuron signaling
GO:0042127 regulation of cell population proliferation
GO:0042129 regulation of T cell proliferation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0042734 presynaptic membrane
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043198 dendritic shaft
GO:0043296 apical junction complex
GO:0043410 positive regulation of MAPK cascade
GO:0043525 positive regulation of neuron apoptotic process
GO:0043588 skin development
GO:0043627 response to estrogen
GO:0044093 positive regulation of molecular function
GO:0044325 transmembrane transporter binding
GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
GO:0044877 protein-containing complex binding
GO:0045177 apical part of cell
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045294 alpha-catenin binding
GO:0045296 cadherin binding
GO:0045453 bone resorption
GO:0045595 regulation of cell differentiation
GO:0045596 negative regulation of cell differentiation
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045667 regulation of osteoblast differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045670 regulation of osteoclast differentiation
GO:0045671 negative regulation of osteoclast differentiation
GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045976 negative regulation of mitotic cell cycle, embryonic
GO:0046332 SMAD binding
GO:0048469 cell maturation
GO:0048471 perinuclear region of cytoplasm
GO:0048489 synaptic vesicle transport
GO:0048513 animal organ development
GO:0048538 thymus development
GO:0048568 embryonic organ development
GO:0048599 oocyte development
GO:0048617 embryonic foregut morphogenesis
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0048660 regulation of smooth muscle cell proliferation
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0050768 negative regulation of neurogenesis
GO:0050808 synapse organization
GO:0050998 nitric-oxide synthase binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051145 smooth muscle cell differentiation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0051884 regulation of timing of anagen
GO:0051973 positive regulation of telomerase activity
GO:0060038 cardiac muscle cell proliferation
GO:0060066 oviduct development
GO:0060070 canonical Wnt signaling pathway
GO:0060173 limb development
GO:0060439 trachea morphogenesis
GO:0060440 trachea formation
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060479 lung cell differentiation
GO:0060484 lung-associated mesenchyme development
GO:0060485 mesenchyme development
GO:0060492 lung induction
GO:0060742 epithelial cell differentiation involved in prostate gland development
GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0060789 hair follicle placode formation
GO:0060916 mesenchymal cell proliferation involved in lung development
GO:0060947 cardiac vascular smooth muscle cell differentiation
GO:0060982 coronary artery morphogenesis
GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation
GO:0061047 positive regulation of branching involved in lung morphogenesis
GO:0061154 endothelial tube morphogenesis
GO:0061198 fungiform papilla formation
GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
GO:0061549 sympathetic ganglion development
GO:0061550 cranial ganglion development
GO:0070369 beta-catenin-TCF7L2 complex
GO:0070411 I-SMAD binding
GO:0070602 regulation of centromeric sister chromatid cohesion
GO:0071260 cellular response to mechanical stimulus
GO:0071363 cellular response to growth factor stimulus
GO:0071681 cellular response to indole-3-methanol
GO:0071944 cell periphery
GO:0072033 renal vesicle formation
GO:0072053 renal inner medulla development
GO:0072054 renal outer medulla development
GO:0072079 nephron tubule formation
GO:0072132 mesenchyme morphogenesis
GO:0072182 regulation of nephron tubule epithelial cell differentiation
GO:0090279 regulation of calcium ion import
GO:0097091 synaptic vesicle clustering
GO:0097718 disordered domain specific binding
GO:0098609 cell-cell adhesion
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098831 presynaptic active zone cytoplasmic component
GO:0099092 postsynaptic density, intracellular component
GO:0140297 DNA-binding transcription factor binding
GO:1901215 negative regulation of neuron death
GO:1903204 negative regulation of oxidative stress-induced neuron death
GO:1904796 regulation of core promoter binding
GO:1904798 positive regulation of core promoter binding
GO:1904888 cranial skeletal system development
GO:1904948 midbrain dopaminergic neuron differentiation
GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:1990138 neuron projection extension
GO:1990226 histone methyltransferase binding
GO:1990314 cellular response to insulin-like growth factor stimulus
GO:1990403 embryonic brain development
GO:1990791 dorsal root ganglion development
GO:1990907 beta-catenin-TCF complex
GO:1990909 Wnt signalosome
GO:2000008 regulation of protein localization to cell surface
GO:2000017 positive regulation of determination of dorsal identity
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2001234 negative regulation of apoptotic signaling pathway

Diseases

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Interactions

148 interactions

InteractorPartnerSourcesPublicationsLink
Ctnnb1Ctnna1BioGRID, mbinfo, MINT10882138 12695331 17113272 32325033 9264463 details
Ctnnb1FERMINT12640114 details
Ctnnb1FYNMINT12640114 details
Ctnnb1SRCMINT12640114 details
Ctnnb1YES1MINT12640114 details
Ctnnb1Ctnnbip1BioGRID, MINT10898789 12874278 details
Ctnnb1Pik3r1BioGRID, IntAct15102471 32325033 details
Ctnnb1Map2k5IntAct15102471 details
Ctnnb1Prop1BioGRID, IntAct16678101 details
Ctnnb1Cdh1BioGRID, DIP, IntAct11348595 11953314 12695331 12874278 14691142 15057752 16293619 16368433 19726720 21730140 23444350 25873176 details
Ctnnb1Lef1BioGRID, IntAct16293619 16309666 17445771 18202148 24748645 details
Ctnnb1CTNNBIP1BioGRID, IntAct12408825 16293619 details
Ctnnb1APCBioGRID, IntAct15327768 16293619 29045831 details
Ctnnb1AXIN1BioGRID, IntAct12417018 16293619 details
Ctnnb1Tax1bp3BioGRID, IntAct12874278 details
Ctnnb1BCL9BioGRID, IntAct17113272 details
Ctnnb1BCL9LBioGRID, IntAct17113272 details
Ctnnb1Carm1MINT17882261 details
Ctnnb1MAPK9IntAct18423204 details
Ctnnb1TCF7L2BioGRID, IntAct12417018 22014570 details
Ctnnb1Axin1BioGRID, IntAct, UniProt10318824 12805222 17053159 18316368 21242974 22682247 24976009 25873176 details
Ctnnb1Gsk3bbhf-ucl, BioGRID10318824 12874278 15327768 19107203 32325033 details
Ctnnb1GSK3Bbhf-ucl, BioGRID, IntAct10481074 12417018 12421363 details
Ctnnb1Axin2BioGRID, IntAct25873176 9554852 details
Ctnnb1Tcf4BioGRID, DIP12874278 15578569 16007074 21103407 details
Ctnnb1SETD1ADIP22723415 details
Ctnnb1Arhgap32BioGRID12531901 details
Ctnnb1Ctnnb1BioGRID20211142 details
Ctnnb1Csnk1eBioGRID12417018 15327768 17053159 details
Ctnnb1Pax3BioGRID20006729 details
Ctnnb1Hmgb2BioGRID19805379 details
Ctnnb1TRAF4BioGRID16969126 details
Ctnnb1BTRCBioGRID12417018 details
Ctnnb1Casp3BioGRID18723680 details
Ctnnb1CREBBPBioGRID11973335 details
Ctnnb1EP300BioGRID11973335 details
Ctnnb1CTNNA1MINT12640114 details
Ctnnb1Tcf7l2BioGRID, MINT10898789 17053159 19503085 19805521 19816403 details
Ctnnb1Grin2bBioGRID, IntAct10862698 16635246 details
Ctnnb1Cdh5MINT18337748 details
Ctnnb1Dact2UniProt21718540 details
Ctnnb1Dact3UniProt21718540 details
Ctnnb1YAP1IntAct23245941 details
Ctnnb1TBX5IntAct23245941 details
Ctnnb1RelaBioGRID, IntAct17445771 23273993 details
Ctnnb1Pth1rIntAct23124878 details
Ctnnb1RaraIntAct24074870 details
Ctnnb1BtrcIntAct25873176 details
Ctnnb1PSEN1BioGRID, IntAct12070348 27036734 details
Ctnnb1TertDIP19571879 details
Ctnnb1Mllt10DIP21103407 details
Ctnnb1Klf4DIP22723415 details
Ctnnb1ASH2LDIP22723415 details
Ctnnb1CTNNA3IntAct23136403 details
Ctnnb1Shank3MINT29531362 details
Ctnnb1PIK3R1BioGRID10477752 details
Ctnnb1PtprfBioGRID8830779 details
Ctnnb1Acp1BioGRID12438242 32325033 details
Ctnnb1MUC1BioGRID15221004 details
Ctnnb1CDH15BioGRID9545347 details
Ctnnb1Sox2BioGRID15781477 details
Ctnnb1JunBioGRID16007074 details
Ctnnb1Smarca4BioGRID15525990 details
Ctnnb1Nf2BioGRID12695331 details
Ctnnb1Cdh2BioGRID12695331 15834408 32325033 details
Ctnnb1Ctnnd1BioGRID12695331 15834408 32325033 details
Ctnnb1PtprqBioGRID16973135 details
Ctnnb1Pcp2BioGRID16973135 details
Ctnnb1Kifap3BioGRID15834408 details
Ctnnb1Kif3bBioGRID15834408 details
Ctnnb1Pin1BioGRID19995909 details
Ctnnb1DcxBioGRID15607950 details
Ctnnb1Usp9xBioGRID15607950 details
Ctnnb1Cops2BioGRID19576224 details
Ctnnb1Tcf7l1BioGRID18202148 details
Ctnnb1Esr1BioGRID18202148 details
Ctnnb1Pou5f1BioGRID22083510 23444350 details
Ctnnb1Cul4aBioGRID17954973 details
Ctnnb1NumbBioGRID17589506 details
Ctnnb1NanogBioGRID23444350 details
Ctnnb1Nr5a1BioGRID12861022 details
Ctnnb1Foxo3BioGRID29717119 details
Ctnnb1TCF4BioGRID15578569 details
Ctnnb1Sox17BioGRID31823782 details
Ctnnb1Grin1BioGRID, IntAct, MINT10862698 16635246 details
Ctnnb1YwhabIntAct16635246 details
Ctnnb1Irs1IntAct15602769 details
Ctnnb1Pecam1IntAct10801826 details
Ctnnb1Mapk8IntAct18423204 details
Ctnnb1Mapk9IntAct18423204 details
Ctnnb1Rac1IntAct18423204 details
Ctnnb1TnikBioGRID, IntAct, MINT19816403 28671696 details
Ctnnb1SNCABioGRID, IntAct18614564 details
Ctnnb1Bbs2IntAct22139371 details
Ctnnb1Rab8aIntAct22139371 details
Ctnnb1Rab11aIntAct22139371 details
Ctnnb1Arl6IntAct22139371 details
Ctnnb1LEF1MINT22373574 details
Ctnnb1Lrrk2BioGRID, IntAct22899650 details
Ctnnb1Lrp6bhf-ucl19107203 details
Ctnnb1TLE1MINT24596249 details
Ctnnb1Trpm7IntAct24855944 details
Ctnnb1FRAT1IntAct10481074 details
Ctnnb1Cyfip2BioGRID, IntAct28671696 details
Ctnnb1Fxr1BioGRID, IntAct28671696 details
Ctnnb1Pex5lBioGRID, IntAct28671696 details
Ctnnb1Pde4dipBioGRID, IntAct28671696 details
Ctnnb1Tsc1BioGRID, IntAct28671696 details
Ctnnb1Dlg4BioGRID, IntAct28671696 details
Ctnnb1Dlgap1BioGRID, IntAct27507650 28671696 details
Ctnnb1Itga3IntAct14691142 details
Ctnnb1PtprmIntAct14691142 details
Ctnnb1EedBioGRID24457600 details
Ctnnb1Syngap1BioGRID27507650 details
Ctnnb1Lnx1BioGRID27889896 details
Ctnnb1Fancd2BioGRID28378742 details
Ctnnb1MycBioGRID23665319 details
Ctnnb1Ppp1r9bBioGRID30562941 details
Ctnnb1Tia1BioGRID27160897 details
Ctnnb1Rgs14BioGRID29518331 details
Ctnnb1Coro1cBioGRID32325033 details
Ctnnb1Ctnnd2BioGRID32325033 details
Ctnnb1Hint1BioGRID32325033 details
Ctnnb1Fscn1BioGRID32325033 details
Ctnnb1OsbpBioGRID32325033 details
Ctnnb1Uchl1BioGRID32325033 details
Ctnnb1Actn1BioGRID32325033 details
Ctnnb1Hcls1BioGRID32325033 details
Ctnnb1Pcsk1BioGRID32325033 details
Ctnnb1Pdlim1BioGRID32325033 details
Ctnnb1Ppm1aBioGRID32325033 details
Ctnnb1Ptk2BioGRID32325033 details
Ctnnb1SrcBioGRID32325033 details
Ctnnb1Tln1BioGRID32325033 details
Ctnnb1Yap1BioGRID32325033 details
Ctnnb1Fermt2BioGRID32325033 details
Ctnnb1Hdac6BioGRID32325033 details
Ctnnb1JupBioGRID32325033 details
Ctnnb1Magi1BioGRID32325033 details
Ctnnb1Magi2BioGRID32325033 details
Ctnnb1Ndrg2BioGRID32325033 details
Ctnnb1VclBioGRID32325033 details
Ctnnb1Frmd5BioGRID32325033 details
Ctnnb1Slc6a4BioGRID32581705 details
Ctnnb1Sox9IntAct23273993 details
Ctnnb1Ascl2IntAct23273993 details
Ctnnb1Lgr5IntAct23273993 details
Ctnnb1UnkBioGRID25737280 details