Entity Details

Primary name AK1CL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91WR5
EntryNameAK1CL_MOUSE
FullNameAldo-keto reductase family 1 member C21
TaxID10090
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesAkr1c21

GO terms

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GOName
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
GO:0004033 aldo-keto reductase (NADP) activity
GO:0005496 steroid binding
GO:0005829 cytosol
GO:0006693 prostaglandin metabolic process
GO:0006694 steroid biosynthetic process
GO:0008202 steroid metabolic process
GO:0016229 steroid dehydrogenase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636 phenanthrene 9,10-monooxygenase activity
GO:0031406 carboxylic acid binding
GO:0032052 bile acid binding
GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042448 progesterone metabolic process
GO:0044597 daunorubicin metabolic process
GO:0044598 doxorubicin metabolic process
GO:0047023 androsterone dehydrogenase activity
GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity
GO:0047042 androsterone dehydrogenase (B-specific) activity
GO:0047086 ketosteroid monooxygenase activity
GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
GO:0047834 D-threo-aldose 1-dehydrogenase activity
GO:0070401 NADP+ binding
GO:0070402 NADPH binding
GO:0072555 17-beta-ketosteroid reductase activity
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity
GO:1902121 lithocholic acid binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR018170 Aldo/keto reductase, conserved siteSiteConserved site
IPR020471 Aldo-keto reductaseFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily
IPR044482 Aldo-keto reductase family 1 member CFamilyFamily

Diseases

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Interactions

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