Entity Details

Primary name Cd28
Entity type gene
Source Source Link

Details

PrimaryID12487
RefseqGene
SymbolCd28
NameCD28 antigen
Chromosome1
Location1 30.52 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCD28_MOUSE

GO terms

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GOName
GO:0001772 immunological synapse
GO:0002020 protease binding
GO:0002863 positive regulation of inflammatory response to antigenic stimulus
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0031295 T cell costimulation
GO:0032733 positive regulation of interleukin-10 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0042102 positive regulation of T cell proliferation
GO:0042110 T cell activation
GO:0042802 identical protein binding
GO:0045060 negative thymic T cell selection
GO:0045066 regulatory T cell differentiation
GO:0045121 membrane raft
GO:0045589 regulation of regulatory T cell differentiation
GO:0045840 positive regulation of mitotic nuclear division
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0048304 positive regulation of isotype switching to IgG isotypes
GO:0050852 T cell receptor signaling pathway
GO:0051897 positive regulation of protein kinase B signaling
GO:0097190 apoptotic signaling pathway
GO:0098636 protein complex involved in cell adhesion

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
Cd28PRKCQInnateDB21964608 details
Cd28Pik3r1DIP17242350 details
Cd28Irf4IntAct23021777 details
Cd28BatfIntAct23021777 details