Entity Details

Primary name Cdc42
Entity type gene
Source Source Link

Details

PrimaryID12540
RefseqGene
SymbolCdc42
Namecell division cycle 42
Chromosome4
Location4 69.83 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCDC42_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000322 storage vacuole
GO:0002040 sprouting angiogenesis
GO:0003161 cardiac conduction system development
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006897 endocytosis
GO:0006911 phagocytosis, engulfment
GO:0007015 actin filament organization
GO:0007030 Golgi organization
GO:0007088 regulation of mitotic nuclear division
GO:0007097 nuclear migration
GO:0007163 establishment or maintenance of cell polarity
GO:0007229 integrin-mediated signaling pathway
GO:0007266 Rho protein signal transduction
GO:0010592 positive regulation of lamellipodium assembly
GO:0016020 membrane
GO:0016197 endosomal transport
GO:0016477 cell migration
GO:0017119 Golgi transport complex
GO:0019901 protein kinase binding
GO:0030031 cell projection assembly
GO:0030141 secretory granule
GO:0030175 filopodium
GO:0030307 positive regulation of cell growth
GO:0030496 midbody
GO:0030742 GTP-dependent protein binding
GO:0031256 leading edge membrane
GO:0031258 lamellipodium membrane
GO:0031274 positive regulation of pseudopodium assembly
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0031996 thioesterase binding
GO:0032427 GBD domain binding
GO:0032467 positive regulation of cytokinesis
GO:0032488 Cdc42 protein signal transduction
GO:0034191 apolipoprotein A-I receptor binding
GO:0034329 cell junction assembly
GO:0034332 adherens junction organization
GO:0034613 cellular protein localization
GO:0035088 establishment or maintenance of apical/basal cell polarity
GO:0036336 dendritic cell migration
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0038189 neuropilin signaling pathway
GO:0039694 viral RNA genome replication
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0043085 positive regulation of catalytic activity
GO:0043197 dendritic spine
GO:0043209 myelin sheath
GO:0043393 regulation of protein binding
GO:0043410 positive regulation of MAPK cascade
GO:0043525 positive regulation of neuron apoptotic process
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045177 apical part of cell
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0045335 phagocytic vesicle
GO:0045740 positive regulation of DNA replication
GO:0046330 positive regulation of JNK cascade
GO:0046847 filopodium assembly
GO:0048549 positive regulation of pinocytosis
GO:0048664 neuron fate determination
GO:0051233 spindle midzone
GO:0051489 regulation of filopodium assembly
GO:0051491 positive regulation of filopodium assembly
GO:0051496 positive regulation of stress fiber assembly
GO:0051647 nucleus localization
GO:0051683 establishment of Golgi localization
GO:0051835 positive regulation of synapse structural plasticity
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
GO:0060047 heart contraction
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060661 submandibular salivary gland formation
GO:0060997 dendritic spine morphogenesis
GO:0061630 ubiquitin protein ligase activity
GO:0071346 cellular response to interferon-gamma
GO:0071944 cell periphery
GO:0072384 organelle transport along microtubule
GO:0072686 mitotic spindle
GO:0090135 actin filament branching
GO:0090316 positive regulation of intracellular protein transport
GO:0098609 cell-cell adhesion
GO:0098685 Schaffer collateral - CA1 synapse
GO:0099159 regulation of modification of postsynaptic structure
GO:0099563 modification of synaptic structure
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:2000251 positive regulation of actin cytoskeleton reorganization

Diseases

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Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
Cdc42Rac1BioGRID, IntAct15102471 32325033 details
Cdc42Pik3cbIntAct23706742 details
Cdc42Arhgap32BioGRID12531901 details
Cdc42Arhgap1BioGRID14966113 details
Cdc42WASIntAct15361624 details
Cdc42Vamp2BioGRID, IntAct15537656 32325033 details
Cdc42PAK1IntAct, MINT18325335 18854161 19893577 details
Cdc42ScribIntAct18329370 details
Cdc42CDC42mbinfo9748241 details
Cdc42Lrrk2BioGRID, IntAct21048939 details
Cdc42Homer2BioGRID10493740 details
Cdc42CitBioGRID10493740 details
Cdc42Dock11BioGRID15710388 details
Cdc42Dock10BioGRID15710388 details
Cdc42Arhgap33BioGRID12773384 details
Cdc42Pafah1b1BioGRID16369480 details
Cdc42Iqgap1BioGRID16369480 32325033 details
Cdc42Srgap1BioGRID11672528 details
Cdc42PrkciIntAct10934474 details
Cdc42Pard6bIntAct10934474 details
Cdc42PARD3IntAct10934474 details
Cdc42Abcg3IntAct17205597 details
Cdc42Hmga2IntAct26045162 details
Cdc42Agap2BioGRID, IntAct28706196 details
Cdc42Fancd2BioGRID28378742 details
Cdc42Ppp1r9bBioGRID30562941 details
Cdc42Rgs14BioGRID29518331 details
Cdc42Ago3BioGRID32325033 details
Cdc42Arhgap44BioGRID32325033 details
Cdc42Dhx9BioGRID32325033 details
Cdc42NclBioGRID32325033 details
Cdc42Rpl28BioGRID32325033 details
Cdc42Rpl6BioGRID32325033 details
Cdc42Rplp0BioGRID32325033 details
Cdc42Ndel1BioGRID32325033 details
Cdc42Ophn1BioGRID32325033 details
Cdc42Rap1bBioGRID32325033 details
Cdc42Rps6BioGRID32325033 details
Cdc42Tuba1aBioGRID32325033 details
Cdc42Tubb5BioGRID32325033 details
Cdc42ApohBioGRID32325033 details
Cdc42Arhgap29BioGRID32325033 details
Cdc42ArhgdiaBioGRID32325033 details
Cdc42Arhgef7BioGRID32325033 details
Cdc42Baiap2BioGRID32325033 details
Cdc42ActbBioGRID32325033 details
Cdc42AhsgBioGRID32325033 details
Cdc42Ddx6BioGRID32325033 details
Cdc42Dync1i1BioGRID32325033 details
Cdc42MaptBioGRID32325033 details
Cdc42Pcbp1BioGRID32325033 details
Cdc42Pde6dBioGRID32325033 details
Cdc42Cdc42ep4BioGRID32325033 details
Cdc42EtfaBioGRID32325033 details
Cdc42Fnbp1BioGRID32325033 details
Cdc42Git1BioGRID32325033 details
Cdc42Lsm14aBioGRID32325033 details
Cdc42Mark4BioGRID32325033 details
Cdc42OcrlBioGRID32325033 details
Cdc42Pak2BioGRID32325033 details
Cdc42Pak3BioGRID32325033 details
Cdc42Ptpn2BioGRID32325033 details
Cdc42Rock2BioGRID32325033 details
Cdc42SarnpBioGRID32325033 details
Cdc42Stau1BioGRID32325033 details
Cdc42Slc6a4BioGRID32581705 details
Cdc42UnkBioGRID25737280 details