Entity Details

Primary name Cdh2
Entity type gene
Source Source Link

Details

PrimaryID12558
RefseqGene
SymbolCdh2
Namecadherin 2
Chromosome18
Location18 10.1 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCADH2_MOUSE

GO terms

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GOName
GO:0003323 type B pancreatic cell development
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005916 fascia adherens
GO:0007043 cell-cell junction assembly
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007416 synapse assembly
GO:0007420 brain development
GO:0008013 beta-catenin binding
GO:0009986 cell surface
GO:0010001 glial cell differentiation
GO:0014032 neural crest cell development
GO:0014069 postsynaptic density
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0021537 telencephalon development
GO:0021987 cerebral cortex development
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030315 T-tubule
GO:0030864 cortical actin cytoskeleton
GO:0031641 regulation of myelination
GO:0032880 regulation of protein localization
GO:0032991 protein-containing complex
GO:0035023 regulation of Rho protein signal transduction
GO:0042383 sarcolemma
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043410 positive regulation of MAPK cascade
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045177 apical part of cell
GO:0045202 synapse
GO:0045294 alpha-catenin binding
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0048514 blood vessel morphogenesis
GO:0048854 brain morphogenesis
GO:0048872 homeostasis of number of cells
GO:0050770 regulation of axonogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0050998 nitric-oxide synthase binding
GO:0051146 striated muscle cell differentiation
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060019 radial glial cell differentiation
GO:0060563 neuroepithelial cell differentiation
GO:0070445 regulation of oligodendrocyte progenitor proliferation
GO:0072659 protein localization to plasma membrane
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090497 mesenchymal cell migration
GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly
GO:0097150 neuronal stem cell population maintenance
GO:0098609 cell-cell adhesion
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:0098978 glutamatergic synapse
GO:0099059 integral component of presynaptic active zone membrane
GO:0099060 integral component of postsynaptic specialization membrane
GO:1902897 regulation of postsynaptic density protein 95 clustering
GO:2000809 positive regulation of synaptic vesicle clustering

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
Cdh2Cdh2DIP20190754 21300292 21572446 details
Cdh2NdnBioGRID22442722 details
Cdh2ArvcfBioGRID11719554 details
Cdh2Grin1BioGRID, IntAct, MINT10862698 16635246 17589506 details
Cdh2Grin2bBioGRID, IntAct10862698 16635246 details
Cdh2PTPN1IntAct11106648 details
Cdh2PTPRMMINT9531566 details
Cdh2RetIntAct21357690 details
Cdh2CdonDIP20160094 details
Cdh2Ctnnd1BioGRID, DIP15834408 24929360 32325033 details
Cdh2Arhgap32BioGRID12531901 details
Cdh2Lrp5BioGRID19075000 details
Cdh2Lrp6BioGRID19075000 details
Cdh2Axin1BioGRID19075000 details
Cdh2Wnt3aBioGRID19075000 details
Cdh2Ctnnb1BioGRID12695331 15834408 32325033 details
Cdh2PtprqBioGRID16973135 details
Cdh2Kifap3BioGRID15834408 details
Cdh2Kif3bBioGRID15834408 details
Cdh2Kif5cBioGRID15834408 details
Cdh2CskBioGRID15861137 details
Cdh2Pik3r1BioGRID15192701 details
Cdh2NumbBioGRID17589506 details
Cdh2NEO1BioGRID15520228 details
Cdh2YwhabIntAct16635246 details
Cdh2YwhazIntAct19562802 details
Cdh2Nphp4BioGRID, IntAct21565611 details
Cdh2Hmga2IntAct26045162 details
Cdh2Gja1DIP21282606 details
Cdh2Cyfip2BioGRID, IntAct28671696 details
Cdh2Fxr1BioGRID, IntAct28671696 details
Cdh2Pex5lBioGRID, IntAct28671696 details
Cdh2Pde4dipBioGRID, IntAct28671696 details
Cdh2TnikBioGRID, IntAct28671696 details
Cdh2Rgs14BioGRID29518331 details
Cdh2Ctnnd2BioGRID32325033 details
Cdh2Ctnna1BioGRID32325033 details
Cdh2Gna13BioGRID32325033 details
Cdh2JupBioGRID32325033 details
Cdh2Cdh11BioGRID32325033 details
Cdh2Pkp4BioGRID32325033 details
Cdh2PtprkBioGRID32325033 details
Cdh2Slc6a4BioGRID32581705 details