Entity Details

Primary name Cdk2
Entity type gene
Source Source Link

Details

PrimaryID12566
RefseqGene
SymbolCdk2
Namecyclin-dependent kinase 2
Chromosome10
Location10
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCDK2_MOUSE

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000287 magnesium ion binding
GO:0000307 cyclin-dependent protein kinase holoenzyme complex
GO:0000781 chromosome, telomeric region
GO:0000793 condensed chromosome
GO:0000805 X chromosome
GO:0000806 Y chromosome
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006468 protein phosphorylation
GO:0006813 potassium ion transport
GO:0007099 centriole replication
GO:0007165 signal transduction
GO:0008284 positive regulation of cell population proliferation
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0010468 regulation of gene expression
GO:0015030 Cajal body
GO:0016301 kinase activity
GO:0016572 histone phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0019904 protein domain specific binding
GO:0030332 cyclin binding
GO:0032298 positive regulation of DNA-dependent DNA replication initiation
GO:0032869 cellular response to insulin stimulus
GO:0043231 intracellular membrane-bounded organelle
GO:0044877 protein-containing complex binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051591 response to cAMP
GO:0051602 response to electrical stimulus
GO:0060968 regulation of gene silencing
GO:0097123 cyclin A1-CDK2 complex
GO:0097124 cyclin A2-CDK2 complex
GO:0097134 cyclin E1-CDK2 complex
GO:0097135 cyclin E2-CDK2 complex
GO:0097472 cyclin-dependent protein kinase activity
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Diseases

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Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
Cdk2Ccna2BioGRID, IntAct10068472 16627785 18635963 19592082 22898779 8226784 8547220 details
Cdk2Ccne1BioGRID, IntAct, MINT12970760 14627988 15155733 15749021 16102793 16627785 17699765 18356301 18635963 19592082 20150892 8226784 8769642 details
Cdk2RB1BioGRID, IntAct16627785 23079656 details
Cdk2H1-1BioGRID18667424 details
Cdk2Rb1BioGRID16102793 18356301 details
Cdk2Ccna1BioGRID12121977 15155733 15707957 18356301 details
Cdk2H1-5BioGRID16120603 17699765 details
Cdk2Cdkn1bBioGRID11328857 16102793 22898779 8033213 8822197 details
Cdk2Bcl2BioGRID16102793 details
Cdk2Trp53BioGRID16102793 details
Cdk2H1f0BioGRID14561402 details
Cdk2H1-0BioGRID11463824 12466960 details
Cdk2LtbBioGRID7604037 details
Cdk2H1f1BioGRID12007403 14627988 15707957 15749021 17371838 8226784 8547220 details
Cdk2CebpaBioGRID15107404 20516642 details
Cdk2Npm1BioGRID16376875 details
Cdk2H1f2BioGRID12970760 22898779 9281369 details
Cdk2H1f5BioGRID16627785 details
Cdk2Brca2BioGRID25218637 details
Cdk2CcncDIP25344755 details
Cdk2Cdkn1aBioGRID12970760 15107404 15155733 15707957 18356301 18729080 9488036 details
Cdk2PuraBioGRID15707957 details
Cdk2Cdc6BioGRID18356301 details
Cdk2Smn1BioGRID12420317 details
Cdk2Ccnd2BioGRID9584157 details
Cdk2PcnaBioGRID12970760 details
Cdk2Pla2g4aBioGRID26303530 details
Cdk2Dppa3BioGRID28712289 details
Cdk2Ccnd1IntAct16413469 details
Cdk2CDKN1BIntAct21423803 details
Cdk2Ppp1ccBioGRID17274640 details
Cdk2BrafBioGRID27034005 details
Cdk2Atxn1BioGRID30457570 details