Entity Details

Primary name Cdk5
Entity type gene
Source Source Link

Details

PrimaryID12568
RefseqGene
SymbolCdk5
Namecyclin-dependent kinase 5
Chromosome5
Location5 11.73 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCDK5_MOUSE

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0001764 neuron migration
GO:0001934 positive regulation of protein phosphorylation
GO:0001963 synaptic transmission, dopaminergic
GO:0002039 p53 binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005176 ErbB-2 class receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0006913 nucleocytoplasmic transport
GO:0006915 apoptotic process
GO:0007005 mitochondrion organization
GO:0007160 cell-matrix adhesion
GO:0007409 axonogenesis
GO:0007416 synapse assembly
GO:0007519 skeletal muscle tissue development
GO:0008045 motor neuron axon guidance
GO:0008092 cytoskeletal protein binding
GO:0008306 associative learning
GO:0008542 visual learning
GO:0009611 response to wounding
GO:0014044 Schwann cell development
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016301 kinase activity
GO:0016310 phosphorylation
GO:0016477 cell migration
GO:0016533 protein kinase 5 complex
GO:0016572 histone phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019233 sensory perception of pain
GO:0019901 protein kinase binding
GO:0021537 telencephalon development
GO:0021549 cerebellum development
GO:0021695 cerebellar cortex development
GO:0021697 cerebellar cortex formation
GO:0021766 hippocampus development
GO:0021819 layer formation in cerebral cortex
GO:0021954 central nervous system neuron development
GO:0021987 cerebral cortex development
GO:0022038 corpus callosum development
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030175 filopodium
GO:0030182 neuron differentiation
GO:0030334 regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030517 negative regulation of axon extension
GO:0030549 acetylcholine receptor activator activity
GO:0030866 cortical actin cytoskeleton organization
GO:0030900 forebrain development
GO:0031175 neuron projection development
GO:0031397 negative regulation of protein ubiquitination
GO:0031594 neuromuscular junction
GO:0031914 negative regulation of synaptic plasticity
GO:0032092 positive regulation of protein binding
GO:0032801 receptor catabolic process
GO:0034352 positive regulation of glial cell apoptotic process
GO:0035249 synaptic transmission, glutamatergic
GO:0035418 protein localization to synapse
GO:0042220 response to cocaine
GO:0042501 serine phosphorylation of STAT protein
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043113 receptor clustering
GO:0043125 ErbB-3 class receptor binding
GO:0043204 perikaryon
GO:0043525 positive regulation of neuron apoptotic process
GO:0045055 regulated exocytosis
GO:0045786 negative regulation of cell cycle
GO:0045860 positive regulation of protein kinase activity
GO:0045861 negative regulation of proteolysis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0046777 protein autophosphorylation
GO:0046826 negative regulation of protein export from nucleus
GO:0046875 ephrin receptor binding
GO:0048148 behavioral response to cocaine
GO:0048167 regulation of synaptic plasticity
GO:0048488 synaptic vesicle endocytosis
GO:0048489 synaptic vesicle transport
GO:0048511 rhythmic process
GO:0048709 oligodendrocyte differentiation
GO:0048812 neuron projection morphogenesis
GO:0048813 dendrite morphogenesis
GO:0050321 tau-protein kinase activity
GO:0051301 cell division
GO:0051402 neuron apoptotic process
GO:0051879 Hsp90 protein binding
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060078 regulation of postsynaptic membrane potential
GO:0060079 excitatory postsynaptic potential
GO:0061001 regulation of dendritic spine morphogenesis
GO:0070509 calcium ion import
GO:0090314 positive regulation of protein targeting to membrane
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098883 synapse pruning
GO:0098978 glutamatergic synapse
GO:0099533 positive regulation of presynaptic cytosolic calcium concentration
GO:0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901215 negative regulation of neuron death
GO:1901216 positive regulation of neuron death
GO:1901387 positive regulation of voltage-gated calcium channel activity
GO:1903076 regulation of protein localization to plasma membrane
GO:1904646 cellular response to amyloid-beta

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
Cdk5H1f0BioGRID11343650 details
Cdk5Stub1BioGRID26206088 details
Cdk5H1-1BioGRID26206088 details
Cdk5H1f1BioGRID31687929 details
Cdk5Per2BioGRID31687929 details
Cdk5MaptBioGRID23362255 30068389 details
Cdk5Dab1BioGRID12077184 16529723 details
Cdk5Cdk5r1BioGRID, DIP, MINT12496365 17341134 18325333 details
Cdk5Fynmbinfo12372285 details
Cdk5PuraBioGRID12972605 32325033 details
Cdk5NefhBioGRID11343650 32325033 details
Cdk5Lrrk2BioGRID26268594 details
Cdk5Dppa3BioGRID28712289 details
Cdk5Septin5BioGRID18385322 details
Cdk5PLXNA2mbinfo12372285 details
Cdk5Camk2aIntAct24725413 details
Cdk5Hmga2IntAct26045162 details
Cdk5Ntrk2DIP17341134 details
Cdk5Esyt1DIP19255425 details
Cdk5Tsc1BioGRID, IntAct28671696 details
Cdk5Dlg4BioGRID, IntAct27507650 28671696 details
Cdk5Dlgap1BioGRID, IntAct27507650 28671696 details
Cdk5Agap2BioGRID, IntAct28706196 details
Cdk5Wdtc1BioGRID27113764 details
Cdk5Cables2BioGRID32325033 details
Cdk5Cct3BioGRID32325033 details
Cdk5GakBioGRID32325033 details
Cdk5Htra2BioGRID32325033 details
Cdk5NesBioGRID32325033 details
Cdk5Ppp1r2BioGRID32325033 details
Cdk5Stip1BioGRID32325033 details
Cdk5Trap1BioGRID32325033 details
Cdk5Wasf1BioGRID32325033 details
Cdk5AmphBioGRID32325033 details
Cdk5Cdkn1bBioGRID32325033 details
Cdk5Stxbp1BioGRID32325033 details
Cdk5Syn1BioGRID32325033 details
Cdk5Cdk5rap2BioGRID32325033 details
Cdk5FibpBioGRID32325033 details
Cdk5Fsd1BioGRID32325033 details
Cdk5Ndel1BioGRID32325033 details
Cdk5Ppp1r1bBioGRID32325033 details
Cdk5Ptpn2BioGRID32325033 details