Entity Details

Primary name Cdkn1b
Entity type gene
Source Source Link

Details

PrimaryID12576
RefseqGene
SymbolCdkn1b
Namecyclin-dependent kinase inhibitor 1B
Chromosome6
Location6 65.77 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCDN1B_MOUSE

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001666 response to hypoxia
GO:0001890 placenta development
GO:0004860 protein kinase inhibitor activity
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0006813 potassium ion transport
GO:0007096 regulation of exit from mitosis
GO:0007219 Notch signaling pathway
GO:0007507 heart development
GO:0007605 sensory perception of sound
GO:0008219 cell death
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009749 response to glucose
GO:0010942 positive regulation of cell death
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030308 negative regulation of cell growth
GO:0030332 cyclin binding
GO:0030544 Hsp70 protein binding
GO:0031116 positive regulation of microtubule polymerization
GO:0032355 response to estradiol
GO:0032991 protein-containing complex
GO:0033673 negative regulation of kinase activity
GO:0042326 negative regulation of phosphorylation
GO:0042493 response to drug
GO:0043066 negative regulation of apoptotic process
GO:0043200 response to amino acid
GO:0043231 intracellular membrane-bounded organelle
GO:0043434 response to peptide hormone
GO:0044877 protein-containing complex binding
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045786 negative regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045930 negative regulation of mitotic cell cycle
GO:0046686 response to cadmium ion
GO:0048102 autophagic cell death
GO:0048839 inner ear development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051087 chaperone binding
GO:0051271 negative regulation of cellular component movement
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0071236 cellular response to antibiotic
GO:0071285 cellular response to lithium ion
GO:0071407 cellular response to organic cyclic compound
GO:1902746 regulation of lens fiber cell differentiation
GO:1902806 regulation of cell cycle G1/S phase transition
GO:1904030 negative regulation of cyclin-dependent protein kinase activity
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1905179 negative regulation of cardiac muscle tissue regeneration

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
Cdkn1bCDK2BioGRID, DIP10393546 15980415 19276117 details
Cdkn1bSPDYABioGRID12972555 details
Cdkn1bCCNE1BioGRID10393546 15980415 details
Cdkn1bNup50BioGRID10811608 details
Cdkn1bCdk2BioGRID11328857 16102793 22898779 8033213 8822197 details
Cdkn1bCops5BioGRID10086358 11704659 32325033 32456285 details
Cdkn1bSKP2BioGRID15980415 23589337 details
Cdkn1bAKT1BioGRID16780593 details
Cdkn1bMcm7MINT16289477 details
Cdkn1bCdk4BioGRID, DIP, IntAct11967266 16413468 17699765 19276117 8033213 8822197 details
Cdkn1bCcnd1BioGRID, IntAct16413469 17699765 8033213 details
Cdkn1bStmn1BioGRID, IntAct15652749 32325033 details
Cdkn1bRhoaBioGRID, MINT17581634 32325033 details
Cdkn1bJak2BioGRID, I2D21423214 details
Cdkn1bCDK4DIP19276117 details
Cdkn1bRnf123BioGRID15531880 32325033 details
Cdkn1bSkp2BioGRID11463388 details
Cdkn1bCcna2BioGRID8547220 8822197 details
Cdkn1bCcne1BioGRID8033213 8822197 details
Cdkn1bCdk6BioGRID8822197 details
Cdkn1bSkp1BioGRID10585767 32325033 details
Cdkn1bCcnd2BioGRID8033213 details
Cdkn1bCcnd3BioGRID8033213 details
Cdkn1bYWHAQBioGRID17470459 details
Cdkn1bMapk15BioGRID32325033 details
Cdkn1bCamk1BioGRID32325033 details
Cdkn1bCdk5BioGRID32325033 details
Cdkn1bKpna3BioGRID32325033 details
Cdkn1bKpna4BioGRID32325033 details
Cdkn1bKpna6BioGRID32325033 details
Cdkn1bCul1BioGRID32325033 details
Cdkn1bCul4aBioGRID32325033 details
Cdkn1bDdb1BioGRID32325033 details
Cdkn1bFibpBioGRID32325033 details
Cdkn1bRbx1BioGRID32325033 details
Cdkn1bUchl1BioGRID32325033 details
Cdkn1bKpna2BioGRID32325033 details
Cdkn1bMycNTNU18393360 details
Cdkn1bFoxo3NTNU18393360 details
Cdkn1bMaxNTNU18393360 details
Cdkn1bFOXO3NTNU18393360 details
Cdkn1bCdkn1bNTNU18393360 details
Cdkn1bAgo2BioGRID25533351 details