Entity Details

Primary name Cftr
Entity type gene
Source Source Link

Details

PrimaryID12638
RefseqGene
SymbolCftr
Namecystic fibrosis transmembrane conductance regulator
Chromosome6
Location6 8.1 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCFTR_MOUSE

GO terms

Show/Hide Table
GOName
GO:0005254 chloride channel activity
GO:0005260 intracellularly ATP-gated chloride channel activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0006695 cholesterol biosynthetic process
GO:0006821 chloride transport
GO:0006833 water transport
GO:0006904 vesicle docking involved in exocytosis
GO:0009986 cell surface
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0015701 bicarbonate transport
GO:0015705 iodide transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0019869 chloride channel inhibitor activity
GO:0019899 enzyme binding
GO:0030165 PDZ domain binding
GO:0030301 cholesterol transport
GO:0030321 transepithelial chloride transport
GO:0030324 lung development
GO:0030425 dendrite
GO:0030659 cytoplasmic vesicle membrane
GO:0031901 early endosome membrane
GO:0032991 protein-containing complex
GO:0033005 positive regulation of mast cell activation
GO:0034707 chloride channel complex
GO:0034976 response to endoplasmic reticulum stress
GO:0035377 transepithelial water transport
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042311 vasodilation
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0043025 neuronal cell body
GO:0045921 positive regulation of exocytosis
GO:0048240 sperm capacitation
GO:0050891 multicellular organismal water homeostasis
GO:0051087 chaperone binding
GO:0051454 intracellular pH elevation
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0055085 transmembrane transport
GO:0060081 membrane hyperpolarization
GO:0071320 cellular response to cAMP
GO:0106138 Sec61 translocon complex binding
GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity
GO:1902476 chloride transmembrane transport
GO:1902943 positive regulation of voltage-gated chloride channel activity
GO:1904322 cellular response to forskolin
GO:1904446 positive regulation of establishment of Sertoli cell barrier
GO:1905460 negative regulation of vascular associated smooth muscle cell apoptotic process
GO:2000077 negative regulation of type B pancreatic cell development

Diseases

Show/Hide Table