Entity Details

Primary name Clock
Entity type gene
Source Source Link

Details

PrimaryID12753
RefseqGene
SymbolClock
Namecircadian locomotor output cycles kaput
Chromosome5
Location5 40.63 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCLOCK_MOUSE

GO terms

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GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005694 chromosome
GO:0005726 perichromatin fibrils
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006473 protein acetylation
GO:0007283 spermatogenesis
GO:0007623 circadian rhythm
GO:0031490 chromatin DNA binding
GO:0032922 circadian regulation of gene expression
GO:0033391 chromatoid body
GO:0042634 regulation of hair cycle
GO:0042752 regulation of circadian rhythm
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0050729 positive regulation of inflammatory response
GO:0050796 regulation of insulin secretion
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051775 response to redox state
GO:0070888 E-box binding
GO:0071479 cellular response to ionizing radiation
GO:1990513 CLOCK-BMAL transcription complex
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000074 regulation of type B pancreatic cell development
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
ClockPrkcaMINT17347670 details
ClockPrkcgMINT17347670 details
ClockArntlBioGRID, DIP, IntAct, MINT, UniProt14701732 16606840 16717091 16777965 17347670 18075593 18662546 18662547 20211142 20832105 20840750 21113167 22441692 22653727 23555304 23735699 24737000 25961797 26323038 26562092 28388406 30683868 9704006 details
ClockPer2BioGRID, IntAct14701732 16717091 18430226 18662546 20832105 21113167 21680841 22274616 23555304 32325033 details
ClockCry1BioGRID, DIP, IntAct14701732 16717091 16777965 18075593 18430226 18662546 23555304 25127877 25961797 details
ClockSirt1BioGRID, IntAct18662546 18662547 details
ClockARNTBioGRID, IntAct9704006 details
ClockPARP1IntAct20832105 details
ClockPPP1CCIntAct23555304 details
ClockCsnk1eIntAct23555304 details
ClockPPP1CAIntAct23555304 details
ClockNR1D2IntAct23555304 details
ClockPPP2R1BIntAct23555304 details
ClockRORCIntAct23555304 details
ClockPPP2R5DIntAct23555304 details
ClockPPP1CBIntAct23555304 details
ClockCSNK2BIntAct23555304 details
ClockCipcIntAct23555304 details
ClockNPAS2IntAct23555304 details
ClockBhlhe41IntAct23555304 details
ClockBHLHE40IntAct23555304 details
ClockCry2BioGRID, IntAct14701732 16717091 23555304 details
ClockPPP2R5EIntAct23555304 details
ClockDBPIntAct23555304 details
ClockArntl2DIP25961797 details
ClockH4f16BioGRID16678094 details
ClockKMT2ADIP21113167 details
ClockDdb1DIP26323038 details
ClockPer1BioGRID14701732 16717091 21680841 32325033 details
ClockPer3BioGRID14701732 32325033 details
ClockEzh2BioGRID16717091 details
ClockKat2bBioGRID16678094 details
ClockKat5BioGRID16678094 details
ClockRae1BioGRID30683868 details
ClockNup98BioGRID30683868 details
ClockWdr76DIP26323038 details
ClockCRY1IntAct28388406 details
ClockPrdm16MINT29320702 details
ClockAbt1BioGRID32325033 details
ClockAjubaBioGRID32325033 details
ClockArid5aBioGRID32325033 details
ClockEp300BioGRID32325033 details
ClockDeaf1BioGRID32325033 details
ClockRb1BioGRID32325033 details
ClockRcor2BioGRID32325033 details
ClockTbl1xBioGRID32325033 details
ClockWwtr1BioGRID32325033 details
ClockZbtb7bBioGRID32098917 details
ClockDbpBioGRID, IntAct18662547 21113167 28388406 details