Entity Details

Primary name Csk
Entity type gene
Source Source Link

Details

PrimaryID12988
RefseqGene
SymbolCsk
Namec-src tyrosine kinase
Chromosome9
Location9 31.18 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsCSK_MOUSE

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0007420 brain development
GO:0008285 negative regulation of cell population proliferation
GO:0010989 negative regulation of low-density lipoprotein particle clearance
GO:0016740 transferase activity
GO:0019903 protein phosphatase binding
GO:0032715 negative regulation of interleukin-6 production
GO:0033673 negative regulation of kinase activity
GO:0034236 protein kinase A catalytic subunit binding
GO:0034332 adherens junction organization
GO:0035556 intracellular signal transduction
GO:0042802 identical protein binding
GO:0042997 negative regulation of Golgi to plasma membrane protein transport
GO:0043406 positive regulation of MAP kinase activity
GO:0045121 membrane raft
GO:0045779 negative regulation of bone resorption
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048709 oligodendrocyte differentiation
GO:0050765 negative regulation of phagocytosis
GO:0050863 regulation of T cell activation
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway
GO:0070064 proline-rich region binding
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071375 cellular response to peptide hormone stimulus

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
CskPag1BioGRID, IntAct16920712 26512138 details
CskCskBioGRID15861137 details
CskPtpn18MINT11158295 details
CskDok2MINT15831486 details
CskDok1BioGRID, IntAct20697350 9221755 details
CskCdh5BioGRID, MINT15861137 details
CskCav1MINT11805080 details
CskPik3caIntAct27474268 details
CskPrag1BioGRID20697350 details
CskCdh2BioGRID15861137 details
CskItgb3BioGRID24558484 details
CskCSKBioGRID, IntAct20360068 details
CskCd44MINT11369760 details
CskLMAN2LBioGRID, IntAct26496610 details
CskAFTPHBioGRID, IntAct26496610 details
CskPCGF5BioGRID, IntAct26496610 details
CskCOX11BioGRID, IntAct26496610 details
CskHOMER3BioGRID, IntAct26496610 details
CskHMGA1BioGRID, IntAct26496610 details
CskUQCRC2BioGRID, IntAct26496610 details
CskFRYLBioGRID, IntAct26496610 details
CskQSER1BioGRID, IntAct26496610 details
CskEBNA1BP2BioGRID, IntAct26496610 details
CskTSC22D3BioGRID, IntAct26496610 details
CskPLCG2BioGRID, IntAct26496610 details
CskCAMK2GBioGRID, IntAct26496610 details
CskTJP2BioGRID, IntAct26496610 details
CskZNF668BioGRID, IntAct26496610 details
CskSH3GLB1BioGRID, IntAct26496610 details
CskITIH6BioGRID, IntAct26496610 details
CskCELF2BioGRID, IntAct26496610 details
CskKIAA1522BioGRID, IntAct26496610 details
CskTRIM21BioGRID, IntAct26496610 details
CskPYM1BioGRID, IntAct26496610 details
CskRABGAP1LBioGRID, IntAct26496610 details
CskZFYVE26BioGRID, IntAct26496610 details
CskRAD52BioGRID, IntAct26496610 details
CskCblIntAct27474268 details
CskCblbIntAct27474268 details
CskCd5IntAct27474268 details
CskAtg16l1BioGRID30196744 details