Entity Details

Primary name Ddit3
Entity type gene
Source Source Link

Details

PrimaryID13198
RefseqGene
SymbolDdit3
NameDNA-damage inducible transcript 3
Chromosome10
Location10
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsDDIT3_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001955 blood vessel maturation
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0006983 ER overload response
GO:0006986 response to unfolded protein
GO:0007605 sensory perception of sound
GO:0008134 transcription factor binding
GO:0008140 cAMP response element binding protein binding
GO:0009948 anterior/posterior axis specification
GO:0010506 regulation of autophagy
GO:0016055 Wnt signaling pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032689 negative regulation of interferon-gamma production
GO:0032700 negative regulation of interleukin-17 production
GO:0032713 negative regulation of interleukin-4 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032792 negative regulation of CREB transcription factor activity
GO:0032993 protein-DNA complex
GO:0034263 positive regulation of autophagy in response to ER overload
GO:0034976 response to endoplasmic reticulum stress
GO:0036488 CHOP-C/EBP complex
GO:0042594 response to starvation
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043392 negative regulation of DNA binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043522 leucine zipper domain binding
GO:0043525 positive regulation of neuron apoptotic process
GO:0045454 cell redox homeostasis
GO:0045599 negative regulation of fat cell differentiation
GO:0045662 negative regulation of myoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051898 negative regulation of protein kinase B signaling
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0072655 establishment of protein localization to mitochondrion
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090575 RNA polymerase II transcription regulator complex
GO:0120163 negative regulation of cold-induced thermogenesis
GO:0140416 transcription regulator inhibitor activity
GO:1901216 positive regulation of neuron death
GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:1990442 intrinsic apoptotic signaling pathway in response to nitrosative stress
GO:1990617 CHOP-ATF4 complex
GO:1990622 CHOP-ATF3 complex
GO:2000016 negative regulation of determination of dorsal identity
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
Ddit3CebpaBioGRID, IntAct20211142 26167872 details
Ddit3Cers2BioGRID, IntAct20211142 details
Ddit3Atf4DIP23624402 details