Entity Details

Primary name Dlg1
Entity type gene
Source Source Link

Details

PrimaryID13383
RefseqGene
SymbolDlg1
Namediscs large MAGUK scaffold protein 1
Chromosome16
Location16 22.4 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsDLG1_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001771 immunological synapse formation
GO:0001772 immunological synapse
GO:0001935 endothelial cell proliferation
GO:0002088 lens development in camera-type eye
GO:0005604 basement membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0007015 actin filament organization
GO:0007268 chemical synaptic transmission
GO:0008022 protein C-terminus binding
GO:0008104 protein localization
GO:0008284 positive regulation of cell population proliferation
GO:0008360 regulation of cell shape
GO:0009898 cytoplasmic side of plasma membrane
GO:0009925 basal plasma membrane
GO:0014069 postsynaptic density
GO:0015459 potassium channel regulator activity
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0019894 kinesin binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030054 cell junction
GO:0030165 PDZ domain binding
GO:0030315 T-tubule
GO:0030425 dendrite
GO:0030432 peristalsis
GO:0030672 synaptic vesicle membrane
GO:0030838 positive regulation of actin filament polymerization
GO:0030866 cortical actin cytoskeleton organization
GO:0030953 astral microtubule organization
GO:0031253 cell projection membrane
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031579 membrane raft organization
GO:0031594 neuromuscular junction
GO:0031641 regulation of myelination
GO:0032147 activation of protein kinase activity
GO:0032880 regulation of protein localization
GO:0033268 node of Ranvier
GO:0033270 paranode region of axon
GO:0034629 cellular protein-containing complex localization
GO:0035255 ionotropic glutamate receptor binding
GO:0035748 myelin sheath abaxonal region
GO:0040018 positive regulation of multicellular organism growth
GO:0042110 T cell activation
GO:0042130 negative regulation of T cell proliferation
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0042982 amyloid precursor protein metabolic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043113 receptor clustering
GO:0043219 lateral loop
GO:0043268 positive regulation of potassium ion transport
GO:0043622 cortical microtubule organization
GO:0044325 transmembrane transporter binding
GO:0045121 membrane raft
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0048608 reproductive structure development
GO:0048639 positive regulation of developmental growth
GO:0048704 embryonic skeletal system morphogenesis
GO:0048729 tissue morphogenesis
GO:0048745 smooth muscle tissue development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051660 establishment of centrosome localization
GO:0051898 negative regulation of protein kinase B signaling
GO:0060022 hard palate development
GO:0060090 molecular adaptor activity
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070830 bicellular tight junction assembly
GO:0072659 protein localization to plasma membrane
GO:0097016 L27 domain binding
GO:0097025 MPP7-DLG1-LIN7 complex
GO:0097060 synaptic membrane
GO:0097120 receptor localization to synapse
GO:0098609 cell-cell adhesion
GO:0098839 postsynaptic density membrane
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0098919 structural constituent of postsynaptic density
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane
GO:1902473 regulation of protein localization to synapse
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1903286 regulation of potassium ion import
GO:1903753 negative regulation of p38MAPK cascade
GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1903764 regulation of potassium ion export across plasma membrane
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
Dlg1Fzd1MINT12067714 details
Dlg1Fzd4MINT12067714 details
Dlg1Fzd7MINT12067714 details
Dlg1Lrfn2IntAct16495444 details
Dlg1Lrfn1IntAct16495444 details
Dlg1NrcamBioGRID, MINT16882004 details
Dlg1NET1BioGRID17938206 details
Dlg1Grin1BioGRID, IntAct10862698 16635246 details
Dlg1Dlg4BioGRID, IntAct19455133 27507650 28671696 32325033 details
Dlg1UbbDIP27070899 details
Dlg1UbcDIP27070899 details
Dlg1Rps27aDIP27070899 details
Dlg1Uba52DIP27070899 details
Dlg1Mapk12DIP27070899 details
Dlg1Crhr1MINT26352593 details
Dlg1Lin7cBioGRID16186258 32325033 details
Dlg1LckBioGRID15699074 details
Dlg1CblBioGRID15699074 details
Dlg1Zap70BioGRID15699074 details
Dlg1WasBioGRID15699074 details
Dlg1Mapk14BioGRID17187070 details
Dlg1Adam10BioGRID17301176 details
Dlg1CaskBioGRID16105026 32325033 details
Dlg1CRHR1BioGRID23576434 details
Dlg1Grin2bIntAct, MINT10862698 16635246 details
Dlg1YwhabIntAct16635246 details
Dlg1Cnksr2BioGRID, IntAct28671696 details
Dlg1Hcn1BioGRID, IntAct28671696 details
Dlg1Syngap1BioGRID, IntAct27507650 28671696 28706196 details
Dlg1TnikBioGRID, IntAct28671696 details
Dlg1Dlgap1BioGRID, IntAct27507650 28671696 details
Dlg1Shank3BioGRID, IntAct27507650 28671696 details
Dlg1Agap2BioGRID28706196 details
Dlg1Ppp1r9bBioGRID30562941 details
Dlg1Asap1BioGRID32325033 details
Dlg1Cadm1BioGRID32325033 details
Dlg1Atp2b4BioGRID32325033 details
Dlg1Epb41BioGRID32325033 details
Dlg1Epb41l2BioGRID32325033 details
Dlg1Map2k2BioGRID32325033 details
Dlg1Pip4k2bBioGRID32325033 details
Dlg1PtenBioGRID32325033 details
Dlg1Snx27BioGRID32325033 details
Dlg1GdaBioGRID32325033 details
Dlg1Pals2BioGRID32325033 details
Dlg1Atp2b2BioGRID32325033 details
Dlg1Apba1BioGRID32325033 details
Dlg1Ctnna1BioGRID32325033 details
Dlg1Gucy1b1BioGRID32325033 details
Dlg1Kcnj10BioGRID32325033 details
Dlg1Lin7aBioGRID32325033 details
Dlg1Slc6a4BioGRID32581705 details