Entity Details

Primary name EOMES_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO54839
EntryNameEOMES_MOUSE
FullNameEomesodermin homolog
TaxID10090
Evidenceevidence at protein level
Length707
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesEomes

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001706 endoderm formation
GO:0001707 mesoderm formation
GO:0001708 cell fate specification
GO:0001714 endodermal cell fate specification
GO:0001824 blastocyst development
GO:0001829 trophectodermal cell differentiation
GO:0001947 heart looping
GO:0002250 adaptive immune response
GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0007492 endoderm development
GO:0009653 anatomical structure morphogenesis
GO:0010002 cardioblast differentiation
GO:0010468 regulation of gene expression
GO:0019827 stem cell population maintenance
GO:0021772 olfactory bulb development
GO:0021796 cerebral cortex regionalization
GO:0021895 cerebral cortex neuron differentiation
GO:0022008 neurogenesis
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0035914 skeletal muscle cell differentiation
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048382 mesendoderm development
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0060809 mesodermal to mesenchymal transition involved in gastrulation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR032385 T-box transcription factor-associatedDomainDomain
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions