Entity Details

Primary name Fas
Entity type gene
Source Source Link

Details

PrimaryID14102
RefseqGene
SymbolFas
NameFas (TNF receptor superfamily member 6)
Chromosome19
Location19 29.48 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-01-16
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTNR6_MOUSE

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0002020 protease binding
GO:0005031 tumor necrosis factor-activated receptor activity
GO:0005516 calmodulin binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0006924 activation-induced cell death of T cells
GO:0006925 inflammatory cell apoptotic process
GO:0007623 circadian rhythm
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0009636 response to toxic substance
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010467 gene expression
GO:0010468 regulation of gene expression
GO:0010626 negative regulation of Schwann cell proliferation
GO:0010942 positive regulation of cell death
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016604 nuclear body
GO:0019724 B cell mediated immunity
GO:0019900 kinase binding
GO:0030141 secretory granule
GO:0031104 dendrite regeneration
GO:0031264 death-inducing signaling complex
GO:0031265 CD95 death-inducing signaling complex
GO:0031334 positive regulation of protein-containing complex assembly
GO:0032872 regulation of stress-activated MAPK cascade
GO:0034198 cellular response to amino acid starvation
GO:0036337 Fas signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042383 sarcolemma
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0045060 negative thymic T cell selection
GO:0045121 membrane raft
GO:0045619 regulation of lymphocyte differentiation
GO:0045637 regulation of myeloid cell differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0048536 spleen development
GO:0050869 negative regulation of B cell activation
GO:0051384 response to glucocorticoid
GO:0051402 neuron apoptotic process
GO:0070227 lymphocyte apoptotic process
GO:0071285 cellular response to lithium ion
GO:0071455 cellular response to hyperoxia
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097049 motor neuron apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097284 hepatocyte apoptotic process
GO:0097440 apical dendrite
GO:0097527 necroptotic signaling pathway
GO:1900148 negative regulation of Schwann cell migration
GO:2001235 positive regulation of apoptotic signaling pathway
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Diseases

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Interactions

13 interactions

InteractorPartnerSourcesPublicationsLink
FasDAXXBioGRID, IntAct, MINT11483955 9215629 details
FasDaxxBioGRID, IntAct, MINT11483955 9215629 details
FasFaf1MINT8524870 details
FasFADDBioGRID, DIP, IntAct10542291 20935634 7536190 details
FasFASIntAct7536190 details
FasUbe2iBioGRID, IntAct11034606 9257699 details
FasHipk3IntAct11034606 details
FasFEM1BBioGRID10542291 details
FasEzrMINT17159908 details
FasFaddBioGRID, IntAct, MINT11978827 17159908 18455983 21382479 details
FasCasp8BioGRID, IntAct, MINT11978827 17159908 18455983 21382479 details
FasPmlBioGRID, IntAct21803845 details
FasFaslBioGRID11978827 details